O'Doherty RM - Search Results

1

Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.

Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Edmunds LR, et al. Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856. Oncotarget. 2016. PMID: 27105497 Free PMC article.

2

c-Myc is required for the CHREBP-dependent activation of glucose-responsive genes.

Zhang P, Metukuri MR, Bindom SM, Prochownik EV, O'Doherty RM, Scott DK. Zhang P, et al. Mol Endocrinol. 2010 Jun;24(6):1274-86. doi: 10.1210/me.2009-0437. Epub 2010 Apr 9. Mol Endocrinol. 2010. PMID: 20382893 Free PMC article.

3

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels.

Stefanovic-Racic M, Perdomo G, Mantell BS, Sipula IJ, Brown NF, O'Doherty RM. Stefanovic-Racic M, et al. Am J Physiol Endocrinol Metab. 2008 May;294(5):E969-77. doi: 10.1152/ajpendo.00497.2007. Epub 2008 Mar 18. Am J Physiol Endocrinol Metab. 2008. PMID: 18349115 Free article.

4

Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance.

Huang W, Metlakunta A, Dedousis N, Zhang P, Sipula I, Dube JJ, Scott DK, O'Doherty RM. Huang W, et al. Diabetes. 2010 Feb;59(2):347-57. doi: 10.2337/db09-0016. Epub 2009 Nov 23. Diabetes. 2010. PMID: 19934001 Free PMC article.

5

Elevated metabolic rate and skeletal muscle oxidative metabolism contribute to the reduced susceptibility of NF-κB p50 null mice to obesity.

Bhatt BA, Dedousis N, Sipula IJ, O'Doherty RM. Bhatt BA, et al. Among authors: o doherty rm. Physiol Rep. 2018 Sep;6(18):e13836. doi: 10.14814/phy2.13836. Physiol Rep. 2018. PMID: 30251338 Free PMC article.

6

Kupffer cells facilitate the acute effects of leptin on hepatic lipid metabolism.

Metlakunta A, Huang W, Stefanovic-Racic M, Dedousis N, Sipula I, O'Doherty RM. Metlakunta A, et al. Am J Physiol Endocrinol Metab. 2017 Jan 1;312(1):E11-E18. doi: 10.1152/ajpendo.00250.2016. Epub 2016 Nov 8. Am J Physiol Endocrinol Metab. 2017. PMID: 27827807 Free PMC article.

7

Adipose tissue-derived free fatty acids initiate myeloid cell accumulation in mouse liver in states of lipid oversupply.

Harmon DB, Wu C, Dedousis N, Sipula IJ, Stefanovic-Racic M, Schoiswohl G, O'Donnell CP, Alonso LC, Kershaw EE, Kelley EE, O'Doherty RM. Harmon DB, et al. Among authors: o doherty rm. Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E758-E770. doi: 10.1152/ajpendo.00172.2018. Epub 2018 Aug 7. Am J Physiol Endocrinol Metab. 2018. PMID: 30086648 Free PMC article.

8

Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity.

Mantell BS, Stefanovic-Racic M, Yang X, Dedousis N, Sipula IJ, O'Doherty RM. Mantell BS, et al. PLoS One. 2011;6(6):e19831. doi: 10.1371/journal.pone.0019831. Epub 2011 Jun 3. PLoS One. 2011. PMID: 21674035 Free PMC article.

9

Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver.

Stefanovic-Racic M, Yang X, Turner MS, Mantell BS, Stolz DB, Sumpter TL, Sipula IJ, Dedousis N, Scott DK, Morel PA, Thomson AW, O'Doherty RM. Stefanovic-Racic M, et al. Diabetes. 2012 Sep;61(9):2330-9. doi: 10.2337/db11-1523. Epub 2012 Jul 30. Diabetes. 2012. PMID: 22851575 Free PMC article.

10

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.

Schoiswohl G, Stefanovic-Racic M, Menke MN, Wills RC, Surlow BA, Basantani MK, Sitnick MT, Cai L, Yazbeck CF, Stolz DB, Pulinilkunnil T, O'Doherty RM, Kershaw EE. Schoiswohl G, et al. Endocrinology. 2015 Oct;156(10):3610-24. doi: 10.1210/en.2015-1322. Epub 2015 Jul 21. Endocrinology. 2015. PMID: 26196542 Free PMC article.

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