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127 results

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Phase I trial of MS-275, a histone deacetylase inhibitor, administered weekly in refractory solid tumors and lymphoid malignancies.
Kummar S, Gutierrez M, Gardner ER, Donovan E, Hwang K, Chung EJ, Lee MJ, Maynard K, Kalnitskiy M, Chen A, Melillo G, Ryan QC, Conley B, Figg WD, Trepel JB, Zwiebel J, Doroshow JH, Murgo AJ. Kummar S, et al. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5411-7. doi: 10.1158/1078-0432.CCR-07-0791. Clin Cancer Res. 2007. PMID: 17875771 Clinical Trial.
Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies.
Kummar S, Gutierrez ME, Gardner ER, Chen X, Figg WD, Zajac-Kaye M, Chen M, Steinberg SM, Muir CA, Yancey MA, Horneffer YR, Juwara L, Melillo G, Ivy SP, Merino M, Neckers L, Steeg PS, Conley BA, Giaccone G, Doroshow JH, Murgo AJ. Kummar S, et al. Among authors: conley ba. Eur J Cancer. 2010 Jan;46(2):340-7. doi: 10.1016/j.ejca.2009.10.026. Epub 2009 Nov 27. Eur J Cancer. 2010. PMID: 19945858 Free PMC article. Clinical Trial.
Development and use of integral assays in clinical trials.
Schilsky RL, Doroshow JH, Leblanc M, Conley BA. Schilsky RL, et al. Among authors: conley ba. Clin Cancer Res. 2012 Mar 15;18(6):1540-6. doi: 10.1158/1078-0432.CCR-11-2202. Clin Cancer Res. 2012. PMID: 22422406 Free PMC article.
Criteria for the use of omics-based predictors in clinical trials.
McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA. McShane LM, et al. Among authors: conley ba. Nature. 2013 Oct 17;502(7471):317-20. doi: 10.1038/nature12564. Nature. 2013. PMID: 24132288 Free PMC article.
Molecular analysis for therapy choice: NCI MATCH.
Conley BA, Doroshow JH. Conley BA, et al. Semin Oncol. 2014 Jun;41(3):297-9. doi: 10.1053/j.seminoncol.2014.05.002. Epub 2014 May 22. Semin Oncol. 2014. PMID: 25023344 No abstract available.
127 results