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Page 1
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.
Laaksonen R, Ekroos K, Sysi-Aho M, Hilvo M, Vihervaara T, Kauhanen D, Suoniemi M, Hurme R, März W, Scharnagl H, Stojakovic T, Vlachopoulou E, Lokki ML, Nieminen MS, Klingenberg R, Matter CM, Hornemann T, Jüni P, Rodondi N, Räber L, Windecker S, Gencer B, Pedersen ER, Tell GS, Nygård O, Mach F, Sinisalo J, Lüscher TF. Laaksonen R, et al. Among authors: hornemann t. Eur Heart J. 2016 Jul 1;37(25):1967-76. doi: 10.1093/eurheartj/ehw148. Epub 2016 Apr 28. Eur Heart J. 2016. PMID: 27125947 Free PMC article.
Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
Griess K, Rieck M, Müller N, Karsai G, Hartwig S, Pelligra A, Hardt R, Schlegel C, Kuboth J, Uhlemeyer C, Trenkamp S, Jeruschke K, Weiss J, Peifer-Weiss L, Xu W, Cames S, Yi X, Cnop M, Beller M, Stark H, Kondadi AK, Reichert AS, Markgraf D, Wammers M, Häussinger D, Kuss O, Lehr S, Eizirik D, Lickert H, Lammert E, Roden M, Winter D, Al-Hasani H, Höglinger D, Hornemann T, Brüning JC, Belgardt BF. Griess K, et al. Among authors: hornemann t. Nat Cell Biol. 2023 Jan;25(1):20-29. doi: 10.1038/s41556-022-01027-2. Epub 2022 Dec 21. Nat Cell Biol. 2023. PMID: 36543979 Free PMC article.
Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction.
Sutter I, Klingenberg R, Othman A, Rohrer L, Landmesser U, Heg D, Rodondi N, Mach F, Windecker S, Matter CM, Lüscher TF, von Eckardstein A, Hornemann T. Sutter I, et al. Among authors: hornemann t. Atherosclerosis. 2016 Mar;246:130-40. doi: 10.1016/j.atherosclerosis.2016.01.003. Epub 2016 Jan 6. Atherosclerosis. 2016. PMID: 26773473
Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy.
Costantino S, Akhmedov A, Melina G, Mohammed SA, Othman A, Ambrosini S, Wijnen WJ, Sada L, Ciavarella GM, Liberale L, Tanner FC, Matter CM, Hornemann T, Volpe M, Mechta-Grigoriou F, Camici GG, Sinatra R, Lüscher TF, Paneni F. Costantino S, et al. Among authors: hornemann t. Eur Heart J. 2019 Mar 21;40(12):997-1008. doi: 10.1093/eurheartj/ehy903. Eur Heart J. 2019. PMID: 30629164
Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature.
Oppi S, Nusser-Stein S, Blyszczuk P, Wang X, Jomard A, Marzolla V, Yang K, Velagapudi S, Ward LJ, Yuan XM, Geiger MA, Guillaumon AT, Othman A, Hornemann T, Rancic Z, Ryu D, Oosterveer MH, Osto E, Lüscher TF, Stein S. Oppi S, et al. Among authors: hornemann t. Eur Heart J. 2020 Mar 1;41(9):995-1005. doi: 10.1093/eurheartj/ehz667. Eur Heart J. 2020. PMID: 31529020
Inhibition of de novo ceramide synthesis by Sirtuin-1 improves beta-cell function and glucose metabolism in type 2 diabetes.
Velagapudi S, Karsai G, Karsai M, Mohammed SA, Montecucco F, Liberale L, Lee H, Carbone F, Francesco Adami G, Yang K, Crucet M, Stein S, Paneni F, Lapikova-Bryhinska T, Jang HD, Kraler S, Vdovenko D, Arnold Züllig R, Camici GG, Kim HS, Laaksonen R, Gerber PA, Hornemann T, Akhmedov A, Lüscher TF. Velagapudi S, et al. Among authors: hornemann t. Cardiovasc Res. 2024 May 13:cvae100. doi: 10.1093/cvr/cvae100. Online ahead of print. Cardiovasc Res. 2024. PMID: 38739545
Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism.
Karuna R, Park R, Othman A, Holleboom AG, Motazacker MM, Sutter I, Kuivenhoven JA, Rohrer L, Matile H, Hornemann T, Stoffel M, Rentsch KM, von Eckardstein A. Karuna R, et al. Among authors: hornemann t. Atherosclerosis. 2011 Dec;219(2):855-63. doi: 10.1016/j.atherosclerosis.2011.08.049. Epub 2011 Sep 6. Atherosclerosis. 2011. PMID: 21944699
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?
Othman A, Rütti MF, Ernst D, Saely CH, Rein P, Drexel H, Porretta-Serapiglia C, Lauria G, Bianchi R, von Eckardstein A, Hornemann T. Othman A, et al. Among authors: hornemann t. Diabetologia. 2012 Feb;55(2):421-31. doi: 10.1007/s00125-011-2384-1. Epub 2011 Nov 29. Diabetologia. 2012. PMID: 22124606
140 results