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Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling.
Zhang XD, Baladandayuthapani V, Lin H, Mulligan G, Li B, Esseltine DW, Qi L, Xu J, Hunziker W, Barlogie B, Usmani SZ, Zhang Q, Crowley J, Hoering A, Shah JJ, Weber DM, Manasanch EE, Thomas SK, Li BZ, Wang HH, Zhang J, Kuiatse I, Tang JL, Wang H, He J, Yang J, Milan E, Cenci S, Ma WC, Wang ZQ, Davis RE, Yang L, Orlowski RZ. Zhang XD, et al. Among authors: cenci s. Cancer Cell. 2016 May 9;29(5):639-652. doi: 10.1016/j.ccell.2016.03.026. Epub 2016 Apr 28. Cancer Cell. 2016. PMID: 27132469 Free PMC article.
The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition.
Bianchi G, Oliva L, Cascio P, Pengo N, Fontana F, Cerruti F, Orsi A, Pasqualetto E, Mezghrani A, Calbi V, Palladini G, Giuliani N, Anderson KC, Sitia R, Cenci S. Bianchi G, et al. Among authors: cenci s. Blood. 2009 Mar 26;113(13):3040-9. doi: 10.1182/blood-2008-08-172734. Epub 2009 Jan 22. Blood. 2009. PMID: 19164601 Free article.
Iron increases the susceptibility of multiple myeloma cells to bortezomib.
Campanella A, Santambrogio P, Fontana F, Frenquelli M, Cenci S, Marcatti M, Sitia R, Tonon G, Camaschella C. Campanella A, et al. Among authors: cenci s. Haematologica. 2013 Jun;98(6):971-9. doi: 10.3324/haematol.2012.074872. Epub 2012 Dec 14. Haematologica. 2013. PMID: 23242599 Free PMC article.
Plasma cells require autophagy for sustainable immunoglobulin production.
Pengo N, Scolari M, Oliva L, Milan E, Mainoldi F, Raimondi A, Fagioli C, Merlini A, Mariani E, Pasqualetto E, Orfanelli U, Ponzoni M, Sitia R, Casola S, Cenci S. Pengo N, et al. Among authors: cenci s. Nat Immunol. 2013 Mar;14(3):298-305. doi: 10.1038/ni.2524. Epub 2013 Jan 27. Nat Immunol. 2013. PMID: 23354484
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari NL, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S. Benasciutti E, et al. Among authors: cenci s. J Bone Miner Res. 2014 Feb;29(2):290-303. doi: 10.1002/jbmr.2090. J Bone Miner Res. 2014. PMID: 24038328 Free article.
Autophagy in Plasma Cell Ontogeny and Malignancy.
Milan E, Fabbri M, Cenci S. Milan E, et al. Among authors: cenci s. J Clin Immunol. 2016 May;36 Suppl 1:18-24. doi: 10.1007/s10875-016-0254-9. Epub 2016 Mar 16. J Clin Immunol. 2016. PMID: 26984755 Free PMC article. Review.
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