Fearns C - Search Results

1

Current and future treatment of amyloid diseases.

Ankarcrona M, Winblad B, Monteiro C, Fearns C, Powers ET, Johansson J, Westermark GT, Presto J, Ericzon BG, Kelly JW. Ankarcrona M, et al. Among authors: fearns c. J Intern Med. 2016 Aug;280(2):177-202. doi: 10.1111/joim.12506. Epub 2016 May 10. J Intern Med. 2016. PMID: 27165517 Free PMC article. Review.

2

The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.

Johnson SM, Connelly S, Fearns C, Powers ET, Kelly JW. Johnson SM, et al. Among authors: fearns c. J Mol Biol. 2012 Aug 10;421(2-3):185-203. doi: 10.1016/j.jmb.2011.12.060. Epub 2012 Jan 5. J Mol Biol. 2012. PMID: 22244854 Free PMC article. Review.

3

Targeting protein aggregation for the treatment of degenerative diseases.

Eisele YS, Monteiro C, Fearns C, Encalada SE, Wiseman RL, Powers ET, Kelly JW. Eisele YS, et al. Among authors: fearns c. Nat Rev Drug Discov. 2015 Nov;14(11):759-80. doi: 10.1038/nrd4593. Epub 2015 Sep 4. Nat Rev Drug Discov. 2015. PMID: 26338154 Free PMC article. Review.

4

Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide.

Fearns C, Kravchenko VV, Ulevitch RJ, Loskutoff DJ. Fearns C, et al. J Exp Med. 1995 Mar 1;181(3):857-66. doi: 10.1084/jem.181.3.857. J Exp Med. 1995. PMID: 7532683 Free PMC article.

5

A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.

Hayashi M, Imanaka-Yoshida K, Yoshida T, Wood M, Fearns C, Tatake RJ, Lee JD. Hayashi M, et al. Among authors: fearns c. Nat Med. 2006 Jan;12(1):128-32. doi: 10.1038/nm1327. Epub 2005 Dec 4. Nat Med. 2006. PMID: 16327803

6

Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.

Lo JF, Hayashi M, Woo-Kim S, Tian B, Huang JF, Fearns C, Takayama S, Zapata JM, Yang Y, Lee JD. Lo JF, et al. Among authors: fearns c. Mol Cell Biol. 2004 Mar;24(6):2226-36. doi: 10.1128/MCB.24.6.2226-2236.2004. Mol Cell Biol. 2004. PMID: 14993262 Free PMC article.

7

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest.

Wang X, McGowan CH, Zhao M, He L, Downey JS, Fearns C, Wang Y, Huang S, Han J. Wang X, et al. Among authors: fearns c. Mol Cell Biol. 2000 Jul;20(13):4543-52. doi: 10.1128/MCB.20.13.4543-4552.2000. Mol Cell Biol. 2000. PMID: 10848581 Free PMC article.

8

MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.

Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, Ulevitch RJ. Pan Q, et al. Among authors: fearns c. J Leukoc Biol. 2007 Jul;82(1):177-83. doi: 10.1189/jlb.1006627. Epub 2007 Apr 2. J Leukoc Biol. 2007. PMID: 17403772

9

Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.

Yuan J, Wang J, Crain K, Fearns C, Kim KA, Hua KL, Gregory PD, Holmes MC, Torbett BE. Yuan J, et al. Among authors: fearns c. Mol Ther. 2012 Apr;20(4):849-59. doi: 10.1038/mt.2011.310. Epub 2012 Jan 24. Mol Ther. 2012. PMID: 22273578 Free PMC article.

10

Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling.

Zhu JH, Chen R, Yi W, Cantin GT, Fearns C, Yang Y, Yates JR 3rd, Lee JD. Zhu JH, et al. Among authors: fearns c. Oncogene. 2008 Apr 17;27(18):2525-31. doi: 10.1038/sj.onc.1210922. Epub 2007 Nov 5. Oncogene. 2008. PMID: 17982484

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