Schroeder RL - Search Results

1

Identification of quinones as novel PIM1 kinase inhibitors.

Schroeder RL, Goyal N, Bratton M, Townley I, Pham NA, Tram P, Stone T, Geathers J, Nguyen K, Sridhar J. Schroeder RL, et al. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3187-3191. doi: 10.1016/j.bmcl.2016.04.079. Epub 2016 Apr 28. Bioorg Med Chem Lett. 2016. PMID: 27173800 Free PMC article.

2

Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion.

Zheng S, Zhong Q, Xi Y, Mottamal M, Zhang Q, Schroeder RL, Sridhar J, He L, McFerrin H, Wang G. Zheng S, et al. Among authors: schroeder rl. J Med Chem. 2014 Aug 14;57(15):6653-67. doi: 10.1021/jm500724x. Epub 2014 Jul 18. J Med Chem. 2014. PMID: 25007006 Free PMC article.

3

Small molecule tyrosine kinase inhibitors of ErbB2/HER2/Neu in the treatment of aggressive breast cancer.

Schroeder RL, Stevens CL, Sridhar J. Schroeder RL, et al. Molecules. 2014 Sep 23;19(9):15196-212. doi: 10.3390/molecules190915196. Molecules. 2014. PMID: 25251190 Free PMC article. Review.

4

Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme.

Sridhar J, Liu J, Komati R, Schroeder R, Jiang Q, Tram P, Riley K, Foroozesh M. Sridhar J, et al. Drug Metab Lett. 2017;10(4):270-277. doi: 10.2174/1872312810666161220155226. Drug Metab Lett. 2017. PMID: 28000546 Free PMC article.

5

Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1).

Schroeder RL, Tram P, Liu J, Foroozesh M, Sridhar J. Schroeder RL, et al. Expert Opin Ther Pat. 2016;26(1):139-47. doi: 10.1517/13543776.2016.1105217. Epub 2015 Oct 29. Expert Opin Ther Pat. 2016. PMID: 26514241 Free PMC article.

6

Identification of New Mono/Dihydroxynaphthoquinone as Lead Agents That Inhibit the Growth of Refractive and Triple-Negative Breast Cancer Cell Lines.

Schroeder R, Sfondouris M, Goyal N, Komati R, Weerathunga A, Gettridge C, Stevens CLK, Jones FE, Sridhar J. Schroeder R, et al. ACS Omega. 2019 Jun 19;4(6):10610-10619. doi: 10.1021/acsomega.9b00929. eCollection 2019 Jun 30. ACS Omega. 2019. PMID: 31460159 Free PMC article.

7

P2Y1 receptor antagonists as novel antithrombotic agents.

Pfefferkorn JA, Choi C, Winters T, Kennedy R, Chi L, Perrin LA, Lu G, Ping YW, McClanahan T, Schroeder R, Leininger MT, Geyer A, Schefzick S, Atherton J. Pfefferkorn JA, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3338-43. doi: 10.1016/j.bmcl.2008.04.028. Epub 2008 Apr 15. Bioorg Med Chem Lett. 2008. PMID: 18445527

8

Evaluation of physicochemical parameters important to the oral bioavailability of peptide-like compounds: implications for the synthesis of renin inhibitors.

Hamilton HW, Steinbaugh BA, Stewart BH, Chan OH, Schmid HL, Schroeder R, Ryan MJ, Keiser J, Taylor MD, Blankley CJ, et al. Hamilton HW, et al. J Med Chem. 1995 Apr 28;38(9):1446-55. doi: 10.1021/jm00009a005. J Med Chem. 1995. PMID: 7739003

9

Butenolide endothelin antagonists with improved aqueous solubility.

Patt WC, Cheng XM, Repine JT, Lee C, Reisdorph BR, Massa MA, Doherty AM, Welch KM, Bryant JW, Flynn MA, Walker DM, Schroeder RL, Haleen SJ, Keiser JA. Patt WC, et al. Among authors: schroeder rl. J Med Chem. 1999 Jun 17;42(12):2162-8. doi: 10.1021/jm980504w. J Med Chem. 1999. PMID: 10377221

10

Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.

Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA. Gould WR, et al. J Thromb Haemost. 2005 Apr;3(4):733-41. doi: 10.1111/j.1538-7836.2005.01186.x. Epub 2005 Feb 23. J Thromb Haemost. 2005. PMID: 15733062 Free article.

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