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Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.
ACS Med Chem Lett. 2016 Mar 1;7(5):487-92. doi: 10.1021/acsmedchemlett.6b00002. eCollection 2016 May 12.
ACS Med Chem Lett. 2016.
PMID: 27190598
Free PMC article.
Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.
Kennedy AJ, Mathews TP, Kharel Y, Field SD, Moyer ML, East JE, Houck JD, Lynch KR, Macdonald TL.
Kennedy AJ, et al. Among authors: houck jd.
J Med Chem. 2011 May 26;54(10):3524-48. doi: 10.1021/jm2001053. Epub 2011 May 2.
J Med Chem. 2011.
PMID: 21495716
Free PMC article.
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A rapid assay for assessment of sphingosine kinase inhibitors and substrates.
Kharel Y, Mathews TP, Kennedy AJ, Houck JD, Macdonald TL, Lynch KR.
Kharel Y, et al. Among authors: houck jd.
Anal Biochem. 2011 Apr 15;411(2):230-5. doi: 10.1016/j.ab.2011.01.003. Epub 2011 Jan 7.
Anal Biochem. 2011.
PMID: 21216217
Free PMC article.
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