Kennedy AJ - Search Results

1

Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.

Houck JD, Dawson TK, Kennedy AJ, Kharel Y, Naimon ND, Field SD, Lynch KR, Macdonald TL. Houck JD, et al. Among authors: kennedy aj. ACS Med Chem Lett. 2016 Mar 1;7(5):487-92. doi: 10.1021/acsmedchemlett.6b00002. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190598 Free PMC article.

2

Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors.

Mathews TP, Kennedy AJ, Kharel Y, Kennedy PC, Nicoara O, Sunkara M, Morris AJ, Wamhoff BR, Lynch KR, Macdonald TL. Mathews TP, et al. Among authors: kennedy pc, kennedy aj. J Med Chem. 2010 Apr 8;53(7):2766-78. doi: 10.1021/jm901860h. J Med Chem. 2010. PMID: 20205392 Free PMC article.

3

Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.

Kennedy AJ, Mathews TP, Kharel Y, Field SD, Moyer ML, East JE, Houck JD, Lynch KR, Macdonald TL. Kennedy AJ, et al. J Med Chem. 2011 May 26;54(10):3524-48. doi: 10.1021/jm2001053. Epub 2011 May 2. J Med Chem. 2011. PMID: 21495716 Free PMC article.

4

A rapid assay for assessment of sphingosine kinase inhibitors and substrates.

Kharel Y, Mathews TP, Kennedy AJ, Houck JD, Macdonald TL, Lynch KR. Kharel Y, et al. Among authors: kennedy aj. Anal Biochem. 2011 Apr 15;411(2):230-5. doi: 10.1016/j.ab.2011.01.003. Epub 2011 Jan 7. Anal Biochem. 2011. PMID: 21216217 Free PMC article.

5

Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX).

East JE, Kennedy AJ, Tomsig JL, De Leon AR, Lynch KR, Macdonald TL. East JE, et al. Among authors: kennedy aj. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7132-6. doi: 10.1016/j.bmcl.2010.09.030. Epub 2010 Sep 15. Bioorg Med Chem Lett. 2010. PMID: 20951039 Free PMC article.

6

Synthesis and Antimicrobial Evaluation of Amixicile-Based Inhibitors of the Pyruvate-Ferredoxin Oxidoreductases of Anaerobic Bacteria and Epsilonproteobacteria.

Kennedy AJ, Bruce AM, Gineste C, Ballard TE, Olekhnovich IN, Macdonald TL, Hoffman PS. Kennedy AJ, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3980-7. doi: 10.1128/AAC.00670-16. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 27090174 Free PMC article.

7

Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model.

Warren CA, van Opstal E, Ballard TE, Kennedy A, Wang X, Riggins M, Olekhnovich I, Warthan M, Kolling GL, Guerrant RL, Macdonald TL, Hoffman PS. Warren CA, et al. Antimicrob Agents Chemother. 2012 Aug;56(8):4103-11. doi: 10.1128/AAC.00360-12. Epub 2012 May 14. Antimicrob Agents Chemother. 2012. PMID: 22585229 Free PMC article.

8

Cytosine-Based TET Enzyme Inhibitors.

Chua GNL, Wassarman KL, Sun H, Alp JA, Jarczyk EI, Kuzio NJ, Bennett MJ, Malachowsky BG, Kruse M, Kennedy AJ. Chua GNL, et al. Among authors: kennedy aj. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185. doi: 10.1021/acsmedchemlett.8b00474. eCollection 2019 Feb 14. ACS Med Chem Lett. 2019. PMID: 30783500 Free PMC article.

9

Additive Impacts of Liveweight and Body Condition Score at Breeding on the Reproductive Performance of Merino and Non-Merino Ewe Lambs.

Thompson AN, Ferguson MB, Kearney GA, Kennedy AJ, Kubeil LJ, Macleay CA, Rosales-Nieto CA, Paganoni BL, Trompf JP. Thompson AN, et al. Among authors: kennedy aj. Animals (Basel). 2024 Mar 12;14(6):867. doi: 10.3390/ani14060867. Animals (Basel). 2024. PMID: 38539967 Free PMC article.

10

Internal Medicine Resident Addiction Training at the Veteran's Health Administration: A Qualitative Evaluation of Site Directors' Response to the 2022 ACGME Requirements.

Richardson C, Daniels K, Confer A, Saxon AJ, Gordon AJ, Liberto J, Albanese AP, Renner J, Edens E, Kennedy AJ. Richardson C, et al. Among authors: kennedy aj. J Gen Intern Med. 2024 Feb 1. doi: 10.1007/s11606-024-08639-4. Online ahead of print. J Gen Intern Med. 2024. PMID: 38302815

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