Amore B - Search Results

1

In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.

Hughes PE, Rex K, Caenepeel S, Yang Y, Zhang Y, Broome MA, Kha HT, Burgess TL, Amore B, Kaplan-Lefko PJ, Moriguchi J, Werner J, Damore MA, Baker D, Choquette DM, Harmange JC, Radinsky R, Kendall R, Dussault I, Coxon A. Hughes PE, et al. Among authors: amore b. Mol Cancer Ther. 2016 Jul;15(7):1568-79. doi: 10.1158/1535-7163.MCT-15-0871. Epub 2016 Apr 19. Mol Cancer Ther. 2016. PMID: 27196782

2

A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors.

Hong DS, Rosen P, Lockhart AC, Fu S, Janku F, Kurzrock R, Khan R, Amore B, Caudillo I, Deng H, Hwang YC, Loberg R, Ngarmchamnanrith G, Beaupre DM, Lee P. Hong DS, et al. Among authors: amore b. Oncotarget. 2015 Jul 30;6(21):18693-706. doi: 10.18632/oncotarget.4472. Oncotarget. 2015. PMID: 26155941 Free PMC article. Clinical Trial.

3

Phase I Study of AMG 337, a Highly Selective Small-molecule MET Inhibitor, in Patients with Advanced Solid Tumors.

Hong DS, LoRusso P, Hamid O, Janku F, Kittaneh M, Catenacci DVT, Chan E, Bekaii-Saab T, Gadgeel SM, Loberg RD, Amore BM, Hwang YC, Tang R, Ngarmchamnanrith G, Kwak EL. Hong DS, et al. Clin Cancer Res. 2019 Apr 15;25(8):2403-2413. doi: 10.1158/1078-0432.CCR-18-1341. Epub 2018 Nov 13. Clin Cancer Res. 2019. PMID: 30425090 Free PMC article.

4

First-in-Human Study of AMG 820, a Monoclonal Anti-Colony-Stimulating Factor 1 Receptor Antibody, in Patients with Advanced Solid Tumors.

Papadopoulos KP, Gluck L, Martin LP, Olszanski AJ, Tolcher AW, Ngarmchamnanrith G, Rasmussen E, Amore BM, Nagorsen D, Hill JS, Stephenson J Jr. Papadopoulos KP, et al. Clin Cancer Res. 2017 Oct 1;23(19):5703-5710. doi: 10.1158/1078-0432.CCR-16-3261. Epub 2017 Jun 27. Clin Cancer Res. 2017. PMID: 28655795 Clinical Trial.

5

A Phase 1 study evaluating AMG 337 in Asian patients with advanced solid tumors.

Yasui H, Go N, Yang H, Amore BM, Jung AS, Doi T. Yasui H, et al. Jpn J Clin Oncol. 2017 Aug 1;47(8):772-776. doi: 10.1093/jjco/hyx067. Jpn J Clin Oncol. 2017. PMID: 28582510 Clinical Trial.

6

Intestinal and hepatic first-pass extraction of the 11β-HSD1 inhibitor AMG 221 in rats with chronic vascular catheters.

Gao Q, Kimura RE, Zhang X, Nam J, Amore BM, Hickman D, Greg Slatter J, Emery MG. Gao Q, et al. Xenobiotica. 2014 Mar;44(3):264-9. doi: 10.3109/00498254.2013.769074. Epub 2013 Mar 21. Xenobiotica. 2014. PMID: 23517558

7

Application of in vivo animal models to characterize the pharmacokinetic and pharmacodynamic properties of drug candidates in discovery settings.

Amore BM, Gibbs JP, Emery MG. Amore BM, et al. Comb Chem High Throughput Screen. 2010 Feb;13(2):207-18. doi: 10.2174/138620710790596808. Comb Chem High Throughput Screen. 2010. PMID: 20053166 Review.

8

Predicting the drug interaction potential of AMG 853, a dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors.

Foti RS, Pearson JT, Wong SL, Zalikowski JA, Boudreaux MD, Prokop SP, Davis JA, Banfield C, Emery MG, Rock DA, Wahlstrom JL, Wienkers LC, Amore BM. Foti RS, et al. Drug Metab Dispos. 2012 Dec;40(12):2239-49. doi: 10.1124/dmd.112.047928. Epub 2012 Aug 28. Drug Metab Dispos. 2012. PMID: 22930276

9

Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose-response model.

Jadhav SB, Crass RL, Chapel S, Kerschnitzki M, Sasiela WJ, Emery MG, Amore BM, Barrett PHR, Watts GF, Catapano AL. Jadhav SB, et al. Among authors: amore bm. Eur Heart J Cardiovasc Pharmacother. 2022 Sep 3;8(6):578-586. doi: 10.1093/ehjcvp/pvab064. Eur Heart J Cardiovasc Pharmacother. 2022. PMID: 34448822 Free PMC article.

10

Absence of effect of steady state bempedoic acid on cardiac repolarization: Results of a thorough QT/QTc study in healthy volunteers.

Amore BM, Cramer CT, MacDougall DE, Sasiela WJ, Emery MG. Amore BM, et al. Clin Transl Sci. 2021 Nov;14(6):2487-2496. doi: 10.1111/cts.13116. Epub 2021 Aug 31. Clin Transl Sci. 2021. PMID: 34463032 Free PMC article. Clinical Trial.

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