Kotake Y - Search Results

1

Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61.

Huang KC, Chen Z, Jiang Y, Akare S, Kolber-Simonds D, Condon K, Agoulnik S, Tendyke K, Shen Y, Wu KM, Mathieu S, Choi HW, Zhu X, Shimizu H, Kotake Y, Gerwick WH, Uenaka T, Woodall-Jappe M, Nomoto K. Huang KC, et al. Among authors: kotake y. Mol Cancer Ther. 2016 Jun;15(6):1208-16. doi: 10.1158/1535-7163.MCT-15-0648. Epub 2016 Mar 29. Mol Cancer Ther. 2016. PMID: 27196783

2

Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.

Nakamura K, Sugumi H, Yamaguchi A, Uenaka T, Kotake Y, Okada T, Kamata J, Niijima J, Nagasu T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Nakamura K, et al. Among authors: kotake y. Mol Cancer Ther. 2002 Jan;1(3):169-75. Mol Cancer Ther. 2002. PMID: 12467211

3

A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.

Nakamura K, Uenaka T, Nagasu T, Sugumi H, Yamaguchi A, Kotake Y, Okada T, Kamata J, Niijima J, Taniguchi T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Nakamura K, et al. Among authors: kotake y. Cancer Sci. 2003 Jan;94(1):119-24. doi: 10.1111/j.1349-7006.2003.tb01362.x. Cancer Sci. 2003. PMID: 12708485 Free article.

4

Synthesis and evaluation of novel pyrimido-acridone, -phenoxadine, and -carbazole as topoisomerase II inhibitors.

Kamata J, Okada T, Kotake Y, Niijima J, Nakamura K, Uenaka T, Yamaguchi A, Tsukahara K, Nagasu T, Koyanagi N, Kitoh K, Yoshimatsu K, Yoshino H, Sugumi H. Kamata J, et al. Among authors: kotake y. Chem Pharm Bull (Tokyo). 2004 Sep;52(9):1071-81. doi: 10.1248/cpb.52.1071. Chem Pharm Bull (Tokyo). 2004. PMID: 15340192 Free article.

5

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

Kotake Y, Sagane K, Owa T, Mimori-Kiyosue Y, Shimizu H, Uesugi M, Ishihama Y, Iwata M, Mizui Y. Kotake Y, et al. Nat Chem Biol. 2007 Sep;3(9):570-5. doi: 10.1038/nchembio.2007.16. Epub 2007 Jul 22. Nat Chem Biol. 2007. PMID: 17643112

6

Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking.

Bao X, Zheng W, Hata Sugi N, Agarwala KL, Xu Q, Wang Z, Tendyke K, Lee W, Parent L, Li W, Cheng H, Shen Y, Taylor N, Dezso Z, Du H, Kotake Y, Zhao N, Wang J, Postema M, Woodall-Jappe M, Takase Y, Uenaka T, Kingston DG, Nomoto K. Bao X, et al. Among authors: kotake y. Cancer Biol Ther. 2015;16(4):589-601. doi: 10.1080/15384047.2015.1019184. Epub 2015 Mar 2. Cancer Biol Ther. 2015. PMID: 25729885 Free PMC article.

7

Biological validation that SF3b is a target of the antitumor macrolide pladienolide.

Yokoi A, Kotake Y, Takahashi K, Kadowaki T, Matsumoto Y, Minoshima Y, Sugi NH, Sagane K, Hamaguchi M, Iwata M, Mizui Y. Yokoi A, et al. Among authors: kotake y. FEBS J. 2011 Dec;278(24):4870-80. doi: 10.1111/j.1742-4658.2011.08387.x. Epub 2011 Oct 31. FEBS J. 2011. PMID: 21981285 Free article.

8

Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor.

Okamoto K, Ito D, Miyazaki K, Watanabe S, Tohyama O, Yokoi A, Ozawa Y, Asano M, Kawamura T, Yamane Y, Nagao S, Funasaka S, Kamata J, Kotake Y, Aoki M, Tsukahara N, Mizui Y, Tanaka I, Sawada K. Okamoto K, et al. Among authors: kotake y. Int J Mol Med. 2012 Apr;29(4):541-9. doi: 10.3892/ijmm.2011.875. Epub 2011 Dec 29. Int J Mol Med. 2012. PMID: 22211243 Free PMC article.

9

Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.

Nagao S, Yamane Y, Funasaka S, Tanaka K, Miyazaki K, Kotake Y, Kamata J, Watanabe-Miyano S, Toyama O, Ozawa Y, Mizui Y, Okamoto K, Ito D. Nagao S, et al. Among authors: kotake y. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29. doi: 10.1016/j.bmc.2014.07.020. Epub 2014 Jul 30. Bioorg Med Chem. 2014. PMID: 25139751

10

Novel sulfonamides as potential, systemically active antitumor agents.

Yoshino H, Ueda N, Niijima J, Sugumi H, Kotake Y, Koyanagi N, Yoshimatsu K, Asada M, Watanabe T, Nagasu T, et al. Yoshino H, et al. Among authors: kotake y. J Med Chem. 1992 Jun 26;35(13):2496-7. doi: 10.1021/jm00091a018. J Med Chem. 1992. PMID: 1619621 No abstract available.

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