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The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.
da Motta LL, Ledaki I, Purshouse K, Haider S, De Bastiani MA, Baban D, Morotti M, Steers G, Wigfield S, Bridges E, Li JL, Knapp S, Ebner D, Klamt F, Harris AL, McIntyre A. da Motta LL, et al. Among authors: wigfield s. Oncogene. 2017 Jan 5;36(1):122-132. doi: 10.1038/onc.2016.184. Epub 2016 Jun 13. Oncogene. 2017. PMID: 27292261 Free PMC article.
Hypoxia-inducible factor-1alpha expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer.
Generali D, Berruti A, Brizzi MP, Campo L, Bonardi S, Wigfield S, Bersiga A, Allevi G, Milani M, Aguggini S, Gandolfi V, Dogliotti L, Bottini A, Harris AL, Fox SB. Generali D, et al. Among authors: wigfield s. Clin Cancer Res. 2006 Aug 1;12(15):4562-8. doi: 10.1158/1078-0432.CCR-05-2690. Clin Cancer Res. 2006. PMID: 16899602 Free article. Clinical Trial.
29 results