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Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells.
Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. Gardner JM, et al. Among authors: metzger tc. Immunity. 2013 Sep 19;39(3):560-72. doi: 10.1016/j.immuni.2013.08.005. Epub 2013 Aug 29. Immunity. 2013. PMID: 23993652 Free PMC article.
Spontaneous development of autoimmune uveitis Is CCR2 dependent.
Chen YF, Zhou D, Metzger T, Gallup M, Jeanne M, Gould DB, Anderson MS, McNamara NA. Chen YF, et al. Am J Pathol. 2014 Jun;184(6):1695-705. doi: 10.1016/j.ajpath.2014.02.024. Epub 2014 Apr 13. Am J Pathol. 2014. PMID: 24736166 Free PMC article.
Myocarditis: a defect in central immune tolerance?
Metzger TC, Anderson MS. Metzger TC, et al. J Clin Invest. 2011 Apr;121(4):1251-3. doi: 10.1172/JCI57211. Epub 2011 Mar 23. J Clin Invest. 2011. PMID: 21436581 Free PMC article.
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. Miller CN, et al. Among authors: metzger tc. Nature. 2018 Jul;559(7715):627-631. doi: 10.1038/s41586-018-0345-2. Epub 2018 Jul 18. Nature. 2018. PMID: 30022164 Free PMC article.
Control of central and peripheral tolerance by Aire.
Metzger TC, Anderson MS. Metzger TC, et al. Immunol Rev. 2011 May;241(1):89-103. doi: 10.1111/j.1600-065X.2011.01008.x. Immunol Rev. 2011. PMID: 21488892 Free PMC article. Review.
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