Huse JT - Search Results

1

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.

Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, Joyce JA. Quail DF, et al. Among authors: huse jt. Science. 2016 May 20;352(6288):aad3018. doi: 10.1126/science.aad3018. Science. 2016. PMID: 27199435 Free PMC article.

2

CSF-1R inhibition alters macrophage polarization and blocks glioma progression.

Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. Pyonteck SM, et al. Among authors: huse jt. Nat Med. 2013 Oct;19(10):1264-72. doi: 10.1038/nm.3337. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056773 Free PMC article.

3

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.

Akkari L, Bowman RL, Tessier J, Klemm F, Handgraaf SM, de Groot M, Quail DF, Tillard L, Gadiot J, Huse JT, Brandsma D, Westerga J, Watts C, Joyce JA. Akkari L, et al. Among authors: huse jt. Sci Transl Med. 2020 Jul 15;12(552):eaaw7843. doi: 10.1126/scitranslmed.aaw7843. Sci Transl Med. 2020. PMID: 32669424

4

Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.

Yan D, Kowal J, Akkari L, Schuhmacher AJ, Huse JT, West BL, Joyce JA. Yan D, et al. Among authors: huse jt. Oncogene. 2017 Oct 26;36(43):6049-6058. doi: 10.1038/onc.2017.261. Epub 2017 Jul 31. Oncogene. 2017. PMID: 28759044 Free PMC article.

5

Genetically engineered mouse models of brain cancer and the promise of preclinical testing.

Huse JT, Holland EC. Huse JT, et al. Brain Pathol. 2009 Jan;19(1):132-43. doi: 10.1111/j.1750-3639.2008.00234.x. Brain Pathol. 2009. PMID: 19076778 Free PMC article. Review.

6

The ABCG2 resistance network of glioblastoma.

Bleau AM, Huse JT, Holland EC. Bleau AM, et al. Among authors: huse jt. Cell Cycle. 2009 Sep 15;8(18):2936-44. Epub 2009 Sep 13. Cell Cycle. 2009. PMID: 19713741 Review.

7

Glioblastoma: molecular analysis and clinical implications.

Huse JT, Holland E, DeAngelis LM. Huse JT, et al. Annu Rev Med. 2013;64:59-70. doi: 10.1146/annurev-med-100711-143028. Epub 2012 Oct 1. Annu Rev Med. 2013. PMID: 23043492

8

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.

Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC. Ozawa T, et al. Among authors: huse jt. Genes Dev. 2010 Oct 1;24(19):2205-18. doi: 10.1101/gad.1972310. Genes Dev. 2010. PMID: 20889717 Free PMC article.

9

Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas.

Squatrito M, Brennan CW, Helmy K, Huse JT, Petrini JH, Holland EC. Squatrito M, et al. Among authors: huse jt. Cancer Cell. 2010 Dec 14;18(6):619-29. doi: 10.1016/j.ccr.2010.10.034. Cancer Cell. 2010. PMID: 21156285 Free PMC article.

10

Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.

Fomchenko EI, Dougherty JD, Helmy KY, Katz AM, Pietras A, Brennan C, Huse JT, Milosevic A, Holland EC. Fomchenko EI, et al. Among authors: huse jt. PLoS One. 2011;6(7):e20605. doi: 10.1371/journal.pone.0020605. Epub 2011 Jul 6. PLoS One. 2011. PMID: 21754979 Free PMC article.

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