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Page 1
Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
Yamniuk AP, Suri A, Krystek SR, Tamura J, Ramamurthy V, Kuhn R, Carroll K, Fleener C, Ryseck R, Cheng L, An Y, Drew P, Grant S, Suchard SJ, Nadler SG, Bryson JW, Sheriff S. Yamniuk AP, et al. Among authors: sheriff s. J Mol Biol. 2016 Jul 17;428(14):2860-79. doi: 10.1016/j.jmb.2016.05.014. Epub 2016 May 21. J Mol Biol. 2016. PMID: 27216500 Free article.
The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.
Ramamurthy V, Yamniuk AP, Lawrence EJ, Yong W, Schneeweis LA, Cheng L, Murdock M, Corbett MJ, Doyle ML, Sheriff S. Ramamurthy V, et al. Among authors: sheriff s. Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1273-81. doi: 10.1107/S2053230X15016416. Epub 2015 Sep 23. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26457518 Free PMC article.
Structures of adnectin/protein complexes reveal an expanded binding footprint.
Ramamurthy V, Krystek SR Jr, Bush A, Wei A, Emanuel SL, Das Gupta R, Janjua A, Cheng L, Murdock M, Abramczyk B, Cohen D, Lin Z, Morin P, Davis JH, Dabritz M, McLaughlin DC, Russo KA, Chao G, Wright MC, Jenny VA, Engle LJ, Furfine E, Sheriff S. Ramamurthy V, et al. Among authors: sheriff s. Structure. 2012 Feb 8;20(2):259-69. doi: 10.1016/j.str.2011.11.016. Structure. 2012. PMID: 22325775 Free article.
Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase γ in three different crystal forms.
Kish K, McDonnell PA, Goldfarb V, Gao M, Metzler WJ, Langley DR, Bryson JW, Kiefer SE, Carpenter B, Kostich WA, Westphal RS, Sheriff S. Kish K, et al. Among authors: sheriff s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jul 1;67(Pt 7):768-74. doi: 10.1107/S1744309111017209. Epub 2011 Jun 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21795790 Free PMC article.
Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold.
Dodd DS, Sheriff S, Chang CJ, Stetsko DK, Phillips LM, Zhang Y, Launay M, Potin D, Vaccaro W, Poss MA, McKinnon M, Barrish JC, Suchard SJ, Murali Dhar TG. Dodd DS, et al. Among authors: sheriff s. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1908-11. doi: 10.1016/j.bmcl.2007.01.036. Epub 2007 Jan 24. Bioorg Med Chem Lett. 2007. PMID: 17291752
Structure and specificity of the anti-digoxin antibody 40-50.
Jeffrey PD, Schildbach JF, Chang CY, Kussie PH, Margolies MN, Sheriff S. Jeffrey PD, et al. Among authors: sheriff s. J Mol Biol. 1995 Apr 28;248(2):344-60. doi: 10.1016/s0022-2836(95)80055-7. J Mol Biol. 1995. PMID: 7739045 Free article.
Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Wang H, Ruan Z, Li JJ, Simpkins LM, Smirk RA, Wu SC, Hutchins RD, Nirschl DS, Van Kirk K, Cooper CB, Sutton JC, Ma Z, Golla R, Seethala R, Salyan ME, Nayeem A, Krystek SR Jr, Sheriff S, Camac DM, Morin PE, Carpenter B, Robl JA, Zahler R, Gordon DA, Hamann LG. Wang H, et al. Among authors: sheriff s. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3168-72. doi: 10.1016/j.bmcl.2008.04.069. Epub 2008 May 1. Bioorg Med Chem Lett. 2008. PMID: 18485702
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).
Watterson SH, Xiao Z, Dodd DS, Tortolani DR, Vaccaro W, Potin D, Launay M, Stetsko DK, Skala S, Davis PM, Lee D, Yang X, McIntyre KW, Balimane P, Patel K, Yang Z, Marathe P, Kadiyala P, Tebben AJ, Sheriff S, Chang CY, Ziemba T, Zhang H, Chen BC, DelMonte AJ, Aranibar N, McKinnon M, Barrish JC, Suchard SJ, Murali Dhar TG. Watterson SH, et al. Among authors: sheriff s. J Med Chem. 2010 May 13;53(9):3814-30. doi: 10.1021/jm100348u. J Med Chem. 2010. PMID: 20405922
279 results