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Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
Yamniuk AP, Suri A, Krystek SR, Tamura J, Ramamurthy V, Kuhn R, Carroll K, Fleener C, Ryseck R, Cheng L, An Y, Drew P, Grant S, Suchard SJ, Nadler SG, Bryson JW, Sheriff S. Yamniuk AP, et al. Among authors: suchard sj. J Mol Biol. 2016 Jul 17;428(14):2860-79. doi: 10.1016/j.jmb.2016.05.014. Epub 2016 May 21. J Mol Biol. 2016. PMID: 27216500 Free article.
Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases.
Xie JH, Yamniuk AP, Borowski V, Kuhn R, Susulic V, Rex-Rabe S, Yang X, Zhou X, Zhang Y, Gillooly K, Brosius R, Ravishankar R, Waggie K, Mink K, Price L, Rehfuss R, Tamura J, An Y, Cheng L, Abramczyk B, Ignatovich O, Drew P, Grant S, Bryson JW, Suchard S, Salter-Cid L, Nadler S, Suri A. Xie JH, et al. J Immunol. 2014 May 1;192(9):4083-92. doi: 10.4049/jimmunol.1303239. Epub 2014 Mar 26. J Immunol. 2014. PMID: 24670803
Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection.
Kim SC, Wakwe W, Higginbotham LB, Mathews DV, Breeden CP, Stephenson AC, Jenkins J, Strobert E, Price K, Price L, Kuhn R, Wang H, Yamniuk A, Suchard S, Farris AB 3rd, Pearson TC, Larsen CP, Ford ML, Suri A, Nadler S, Adams AB. Kim SC, et al. Am J Transplant. 2017 May;17(5):1182-1192. doi: 10.1111/ajt.14197. Epub 2017 Feb 25. Am J Transplant. 2017. PMID: 28097811 Free PMC article.
Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699.
Yang Z, Wang H, Salcedo TW, Suchard SJ, Xie JH, Schneeweis LA, Fleener CA, Calore JD, Shi R, Zhang SX, Rodrigues AD, Car BD, Marathe PH, Nadler SG. Yang Z, et al. Among authors: suchard sj. J Pharmacol Exp Ther. 2015 Dec;355(3):506-15. doi: 10.1124/jpet.115.227249. Epub 2015 Oct 6. J Pharmacol Exp Ther. 2015. PMID: 26442523
Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold.
Dodd DS, Sheriff S, Chang CJ, Stetsko DK, Phillips LM, Zhang Y, Launay M, Potin D, Vaccaro W, Poss MA, McKinnon M, Barrish JC, Suchard SJ, Murali Dhar TG. Dodd DS, et al. Among authors: suchard sj. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1908-11. doi: 10.1016/j.bmcl.2007.01.036. Epub 2007 Jan 24. Bioorg Med Chem Lett. 2007. PMID: 17291752
64 results