Okun I - Search Results

1

AVN-101: A Multi-Target Drug Candidate for the Treatment of CNS Disorders.

Ivachtchenko AV, Lavrovsky Y, Okun I. Ivachtchenko AV, et al. Among authors: okun i. J Alzheimers Dis. 2016 May 25;53(2):583-620. doi: 10.3233/JAD-151146. J Alzheimers Dis. 2016. PMID: 27232215 Free PMC article. Review.

2

AVN-322 is a Safe Orally Bio-Available Potent and Highly Selective Antagonist of 5-HT6R with Demonstrated Ability to Improve Impaired Memory in Animal Models.

Ivachtchenko AV, Ivanenkov YA, Veselov MS, Okun IM. Ivachtchenko AV, et al. Among authors: okun im. Curr Alzheimer Res. 2017;14(3):268-294. doi: 10.2174/1567205013666161108105005. Curr Alzheimer Res. 2017. PMID: 27829340

3

AVN-492, A Novel Highly Selective 5-HT6R Antagonist: Preclinical Evaluation.

Ivachtchenko AV, Okun I, Aladinskiy V, Ivanenkov Y, Koryakova A, Karapetyan R, Mitkin O, Salimov R, Ivashchenko A. Ivachtchenko AV, et al. Among authors: okun i. J Alzheimers Dis. 2017;58(4):1043-1063. doi: 10.3233/JAD-161262. J Alzheimers Dis. 2017. PMID: 28550249

4

From anti-allergic to anti-Alzheimer's: Molecular pharmacology of Dimebon.

Okun I, Tkachenko SE, Khvat A, Mitkin O, Kazey V, Ivachtchenko AV. Okun I, et al. Curr Alzheimer Res. 2010 Mar;7(2):97-112. doi: 10.2174/156720510790691100. Curr Alzheimer Res. 2010. PMID: 19939222

5

Caspase activity modulators as anticancer agents.

Okun I, Balakin KV, Tkachenko SE, Ivachtchenko AV. Okun I, et al. Anticancer Agents Med Chem. 2008 Apr;8(3):322-41. doi: 10.2174/187152008783961914. Anticancer Agents Med Chem. 2008. PMID: 18393791 Review.

6

Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles.

Ivachtchenko AV, Frolov EB, Mitkin OD, Tkachenko SE, Okun IM, Khvat AV. Ivachtchenko AV, et al. Bioorg Med Chem Lett. 2010 Jan 1;20(1):78-82. doi: 10.1016/j.bmcl.2009.11.037. Epub 2009 Nov 14. Bioorg Med Chem Lett. 2010. PMID: 19945877

7

Synthesis and biological study of 3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines as potent and selective serotonin 5-HT6 receptor antagonists.

Ivachtchenko AV, Golovina ES, Kadieva MG, Koryakova AG, Kovalenko SM, Mitkin OD, Okun IM, Ravnyeyko IM, Tkachenko SE, Zaremba OV. Ivachtchenko AV, et al. Bioorg Med Chem. 2010 Jul 15;18(14):5282-90. doi: 10.1016/j.bmc.2010.05.051. Epub 2010 May 24. Bioorg Med Chem. 2010. PMID: 20541425

8

(3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: potent and selective antagonists of the serotonin 5-HT6 receptor.

Ivachtchenko AV, Dmitriev DE, Golovina ES, Kadieva MG, Koryakova AG, Kysil VM, Mitkin OD, Okun IM, Tkachenko SE, Vorobiev AA. Ivachtchenko AV, et al. J Med Chem. 2010 Jul 22;53(14):5186-96. doi: 10.1021/jm100350r. J Med Chem. 2010. PMID: 20560595

9

Novel aryl and heteroaryl substituted N-[3-(4-phenylpiperazin-1-yl)propyl]-1,2,4-oxadiazole-5-carboxamides as selective GSK-3 inhibitors.

Koryakova AG, Ivanenkov YA, Ryzhova EA, Bulanova EA, Karapetian RN, Mikitas OV, Katrukha EA, Kazey VI, Okun I, Kravchenko DV, Lavrovsky YV, Korzinov OM, Ivachtchenko AV. Koryakova AG, et al. Among authors: okun i. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3661-6. doi: 10.1016/j.bmcl.2007.11.121. Epub 2007 Dec 5. Bioorg Med Chem Lett. 2008. PMID: 18502121

10

Antagonists of 5-HT₆ receptors. Substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines and 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[4,3-d]pyrimidines-Synthesis and 'structure-activity' relationship.

Ivachtchenko AV, Golovina ES, Kadieva MG, Kysil VM, Mitkin OD, Vorobiev AA, Okun I. Ivachtchenko AV, et al. Among authors: okun i. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4273-80. doi: 10.1016/j.bmcl.2012.05.036. Epub 2012 May 17. Bioorg Med Chem Lett. 2012. PMID: 22664127

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