Lagace DC - Search Results

1

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program.

Khacho M, Clark A, Svoboda DS, Azzi J, MacLaurin JG, Meghaizel C, Sesaki H, Lagace DC, Germain M, Harper ME, Park DS, Slack RS. Khacho M, et al. Among authors: lagace dc. Cell Stem Cell. 2016 Aug 4;19(2):232-247. doi: 10.1016/j.stem.2016.04.015. Epub 2016 May 26. Cell Stem Cell. 2016. PMID: 27237737 Free article.

2

Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.

Khacho M, Clark A, Svoboda DS, MacLaurin JG, Lagace DC, Park DS, Slack RS. Khacho M, et al. Among authors: lagace dc. Hum Mol Genet. 2017 Sep 1;26(17):3327-3341. doi: 10.1093/hmg/ddx217. Hum Mol Genet. 2017. PMID: 28595361 Free PMC article.

3

Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells.

Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS. Julian LM, et al. Among authors: lagace dc. Cell Stem Cell. 2013 Apr 4;12(4):440-52. doi: 10.1016/j.stem.2013.02.001. Epub 2013 Mar 14. Cell Stem Cell. 2013. PMID: 23499385 Free article.

4

RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus.

Vandenbosch R, Clark A, Fong BC, Omais S, Jaafar C, Dugal-Tessier D, Dhaliwal J, Lagace DC, Park DS, Ghanem N, Slack RS. Vandenbosch R, et al. Among authors: lagace dc. Hippocampus. 2016 Nov;26(11):1379-1392. doi: 10.1002/hipo.22613. Epub 2016 Jul 8. Hippocampus. 2016. PMID: 27325572

5

CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.

Jahani-Asl A, Huang E, Irrcher I, Rashidian J, Ishihara N, Lagace DC, Slack RS, Park DS. Jahani-Asl A, et al. Among authors: lagace dc. Hum Mol Genet. 2015 Aug 15;24(16):4573-83. doi: 10.1093/hmg/ddv188. Epub 2015 May 22. Hum Mol Genet. 2015. PMID: 26002103 Free PMC article.

6

Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury.

Amini M, Ma CL, Farazifard R, Zhu G, Zhang Y, Vanderluit J, Zoltewicz JS, Hage F, Savitt JM, Lagace DC, Slack RS, Beique JC, Baudry M, Greer PA, Bergeron R, Park DS. Amini M, et al. Among authors: lagace dc. J Neurosci. 2013 Mar 27;33(13):5773-84. doi: 10.1523/JNEUROSCI.4247-12.2013. J Neurosci. 2013. PMID: 23536090 Free PMC article.

7

Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease.

Rousseaux MW, Marcogliese PC, Qu D, Hewitt SJ, Seang S, Kim RH, Slack RS, Schlossmacher MG, Lagace DC, Mak TW, Park DS. Rousseaux MW, et al. Among authors: lagace dc. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15918-23. doi: 10.1073/pnas.1205102109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 23019375 Free PMC article.

8

The aPKC-CBP Pathway Regulates Adult Hippocampal Neurogenesis in an Age-Dependent Manner.

Gouveia A, Hsu K, Niibori Y, Seegobin M, Cancino GI, He L, Wondisford FE, Bennett S, Lagace D, Frankland PW, Wang J. Gouveia A, et al. Stem Cell Reports. 2016 Oct 11;7(4):719-734. doi: 10.1016/j.stemcr.2016.08.007. Epub 2016 Sep 8. Stem Cell Reports. 2016. PMID: 27618724 Free PMC article.

9

The aPKC-CBP Pathway Regulates Post-stroke Neurovascular Remodeling and Functional Recovery.

Gouveia A, Seegobin M, Kannangara TS, He L, Wondisford F, Comin CH, Costa LDF, Béïque JC, Lagace DC, Lacoste B, Wang J. Gouveia A, et al. Among authors: lagace dc. Stem Cell Reports. 2017 Dec 12;9(6):1735-1744. doi: 10.1016/j.stemcr.2017.10.021. Epub 2017 Nov 22. Stem Cell Reports. 2017. PMID: 29173896 Free PMC article.

10

Excitable Adult-Generated GABAergic Neurons Acquire Functional Innervation in the Cortex after Stroke.

Kannangara TS, Carter A, Xue Y, Dhaliwal JS, Béïque JC, Lagace DC. Kannangara TS, et al. Among authors: lagace dc. Stem Cell Reports. 2018 Dec 11;11(6):1327-1336. doi: 10.1016/j.stemcr.2018.10.011. Epub 2018 Nov 8. Stem Cell Reports. 2018. PMID: 30416050 Free PMC article.

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