Cho EJ - Search Results

1

Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.

Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: cho ej. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.

2

High-throughput screens for eEF-2 kinase.

Devkota AK, Warthaka M, Edupuganti R, Tavares CD, Johnson WH, Ozpolat B, Cho EJ, Dalby KN. Devkota AK, et al. Among authors: cho ej. J Biomol Screen. 2014 Mar;19(3):445-52. doi: 10.1177/1087057113505204. Epub 2013 Sep 27. J Biomol Screen. 2014. PMID: 24078616

3

Identification and validation of novel PERK inhibitors.

Wang Q, Park J, Devkota AK, Cho EJ, Dalby KN, Ren P. Wang Q, et al. Among authors: cho ej. J Chem Inf Model. 2014 May 27;54(5):1467-75. doi: 10.1021/ci500114r. Epub 2014 May 5. J Chem Inf Model. 2014. PMID: 24745945 Free PMC article.

4

Reversible covalent inhibition of eEF-2K by carbonitriles.

Devkota AK, Edupuganti R, Yan C, Shi Y, Jose J, Wang Q, Kaoud TS, Cho EJ, Ren P, Dalby KN. Devkota AK, et al. Among authors: cho ej. Chembiochem. 2014 Nov 3;15(16):2435-42. doi: 10.1002/cbic.201402321. Epub 2014 Sep 15. Chembiochem. 2014. PMID: 25224652 Free PMC article.

5

Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening.

Tavares CD, Devkota AK, Dalby KN, Cho EJ. Tavares CD, et al. Among authors: cho ej. Methods Mol Biol. 2016;1360:19-33. doi: 10.1007/978-1-4939-3073-9_2. Methods Mol Biol. 2016. PMID: 26501899

6

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells.

Rycaj K, Cho EJ, Liu X, Chao HP, Liu B, Li Q, Devkota AK, Zhang D, Chen X, Moore J, Dalby KN, Tang DG. Rycaj K, et al. Among authors: cho ej. Oncotarget. 2016 Mar 22;7(12):14220-40. doi: 10.18632/oncotarget.7303. Oncotarget. 2016. PMID: 26871947 Free PMC article.

7

Optimization of a Luminescence-Based High-Throughput Screening Assay for Detecting Apyrase Activity.

Veloria JR, Devkota AK, Cho EJ, Dalby KN. Veloria JR, et al. Among authors: cho ej. SLAS Discov. 2017 Jan;22(1):94-101. doi: 10.1177/1087057116675859. Epub 2016 Nov 10. SLAS Discov. 2017. PMID: 27821623 Free article.

8

A scalable lysyl hydroxylase 2 expression system and luciferase-based enzymatic activity assay.

Guo HF, Cho EJ, Devkota AK, Chen Y, Russell W, Phillips GN Jr, Yamauchi M, Dalby KN, Kurie JM. Guo HF, et al. Among authors: cho ej. Arch Biochem Biophys. 2017 Mar 15;618:45-51. doi: 10.1016/j.abb.2017.02.003. Epub 2017 Feb 20. Arch Biochem Biophys. 2017. PMID: 28216326 Free PMC article.

9

Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth.

Edupuganti R, Taliaferro JM, Wang Q, Xie X, Cho EJ, Vidhu F, Ren P, Anslyn EV, Bartholomeusz C, Dalby KN. Edupuganti R, et al. Among authors: cho ej. Bioorg Med Chem. 2017 May 1;25(9):2609-2616. doi: 10.1016/j.bmc.2017.03.018. Epub 2017 Mar 10. Bioorg Med Chem. 2017. PMID: 28351607

10

A Fluorescence-Based High-Throughput Assay for the Identification of Anticancer Reagents Targeting Fructose-1,6-Bisphosphate Aldolase.

Cho EJ, Devkota AK, Stancu G, Edupunganti R, Powis G, Dalby KN. Cho EJ, et al. SLAS Discov. 2018 Jan;23(1):1-10. doi: 10.1177/2472555217726325. Epub 2017 Aug 18. SLAS Discov. 2018. PMID: 28820953 Free article.

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