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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: dalby k. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.
Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses.
Silva RP, Huang Y, Nguyen AW, Hsieh CL, Olaluwoye OS, Kaoud TS, Wilen RE, Qerqez AN, Park JG, Khalil AM, Azouz LR, Le KC, Bohanon AL, DiVenere AM, Liu Y, Lee AG, Amengor DA, Shoemaker SR, Costello SM, Padlan EA, Marqusee S, Martinez-Sobrido L, Dalby KN, D'Arcy S, McLellan JS, Maynard JA. Silva RP, et al. Elife. 2023 Mar 21;12:e83710. doi: 10.7554/eLife.83710. Elife. 2023. PMID: 36942851 Free PMC article.
Fluorescent peptide assays for protein kinases.
Devkota AK, Kaoud TS, Warthaka M, Dalby KN. Devkota AK, et al. Among authors: dalby kn. Curr Protoc Mol Biol. 2010 Jul;Chapter 18:Unit 18.17. doi: 10.1002/0471142727.mb1817s91. Curr Protoc Mol Biol. 2010. PMID: 20583097 Free PMC article.
High-throughput screens for eEF-2 kinase.
Devkota AK, Warthaka M, Edupuganti R, Tavares CD, Johnson WH, Ozpolat B, Cho EJ, Dalby KN. Devkota AK, et al. Among authors: dalby kn. J Biomol Screen. 2014 Mar;19(3):445-52. doi: 10.1177/1087057113505204. Epub 2013 Sep 27. J Biomol Screen. 2014. PMID: 24078616
Identification and validation of novel PERK inhibitors.
Wang Q, Park J, Devkota AK, Cho EJ, Dalby KN, Ren P. Wang Q, et al. Among authors: dalby kn. J Chem Inf Model. 2014 May 27;54(5):1467-75. doi: 10.1021/ci500114r. Epub 2014 May 5. J Chem Inf Model. 2014. PMID: 24745945 Free PMC article.
181 results