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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: edupuganti r. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.
High-throughput screens for eEF-2 kinase.
Devkota AK, Warthaka M, Edupuganti R, Tavares CD, Johnson WH, Ozpolat B, Cho EJ, Dalby KN. Devkota AK, et al. Among authors: edupuganti r. J Biomol Screen. 2014 Mar;19(3):445-52. doi: 10.1177/1087057113505204. Epub 2013 Sep 27. J Biomol Screen. 2014. PMID: 24078616
Reversible covalent inhibition of eEF-2K by carbonitriles.
Devkota AK, Edupuganti R, Yan C, Shi Y, Jose J, Wang Q, Kaoud TS, Cho EJ, Ren P, Dalby KN. Devkota AK, et al. Among authors: edupuganti r. Chembiochem. 2014 Nov 3;15(16):2435-42. doi: 10.1002/cbic.201402321. Epub 2014 Sep 15. Chembiochem. 2014. PMID: 25224652 Free PMC article.
c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun.
Xie X, Kaoud TS, Edupuganti R, Zhang T, Kogawa T, Zhao Y, Chauhan GB, Giannoukos DN, Qi Y, Tripathy D, Wang J, Gray NS, Dalby KN, Bartholomeusz C, Ueno NT. Xie X, et al. Among authors: edupuganti r. Oncogene. 2017 May 4;36(18):2599-2608. doi: 10.1038/onc.2016.417. Epub 2016 Dec 12. Oncogene. 2017. PMID: 27941886 Free PMC article.
Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth.
Jose J, Tavares CDJ, Ebelt ND, Lodi A, Edupuganti R, Xie X, Devkota AK, Kaoud TS, Van Den Berg CL, Anslyn EV, Tiziani S, Bartholomeusz C, Dalby KN. Jose J, et al. Among authors: edupuganti r. ACS Med Chem Lett. 2017 Sep 14;8(10):1072-1076. doi: 10.1021/acsmedchemlett.7b00282. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057053 Free PMC article.
40 results