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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: liddington rc. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.
An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.
Indarte M, Puentes R, Maruggi M, Ihle NT, Grandjean G, Scott M, Ahmed Z, Meuillet EJ, Zang S, Lemos R Jr, Du-Cuny L, Layng FIAL, Correa RG, Bankston LA, Liddington RC, Kirkpatrick L, Powis G. Indarte M, et al. Among authors: liddington rc. Cancer Res. 2019 Jun 15;79(12):3100-3111. doi: 10.1158/0008-5472.CAN-18-2372. Epub 2019 Apr 30. Cancer Res. 2019. PMID: 31040156 Free PMC article.
Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.
Feng Y, Sessions EH, Zhang F, Ban F, Placencio-Hickok V, Ma CT, Zeng FY, Pass I, Terry DB, Cadwell G, Bankston LA, Liddington RC, Chung TDY, Pinkerton AB, Sergienko E, Gleave M, Bhowmick NA, Jackson MR, Cherkasov A, Ronai ZA. Feng Y, et al. Among authors: liddington rc. Cancer Lett. 2019 May 1;449:145-162. doi: 10.1016/j.canlet.2019.02.012. Epub 2019 Feb 14. Cancer Lett. 2019. PMID: 30771432 Free PMC article.
PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
Jeung HC, Puentes R, Aleshin A, Indarte M, Correa RG, Bankston LA, Layng FIAL, Ahmed Z, Wistuba I, Yao Y, Duenas DG, Zhang S, Meuillet EJ, Marassi F, Liddington RC, Kirkpatrick L, Powis G. Jeung HC, et al. Among authors: liddington rc. Exp Cell Res. 2021 Dec 15;409(2):112930. doi: 10.1016/j.yexcr.2021.112930. Epub 2021 Nov 17. Exp Cell Res. 2021. PMID: 34800542 Free PMC article.
Cell adhesion: a FERM grasp of membrane dynamics.
Liddington RC, Bankston LA, de Pereda JM. Liddington RC, et al. Curr Biol. 2003 Feb 4;13(3):R94-5. doi: 10.1016/s0960-9822(03)00035-6. Curr Biol. 2003. PMID: 12573235 Free article.
Correction: An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors.
Indarte M, Puentes R, Maruggi M, Ihle NT, Grandjean G, Scott M, Ahmed Z, Meuillet EJ, Zhang S, Lemos R Jr, Du-Cuny L, Layng FIAL, Correa RG, Bankston LA, Liddington RC, Kirkpatrick L, Powis G. Indarte M, et al. Among authors: liddington rc. Cancer Res. 2019 Oct 15;79(20):5457. doi: 10.1158/0008-5472.CAN-19-2586. Cancer Res. 2019. PMID: 31615811 No abstract available.
Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Stanford SM, Aleshin AE, Zhang V, Ardecky RJ, Hedrick MP, Zou J, Ganji SR, Bliss MR, Yamamoto F, Bobkov AA, Kiselar J, Liu Y, Cadwell GW, Khare S, Yu J, Barquilla A, Chung TDY, Mustelin T, Schenk S, Bankston LA, Liddington RC, Pinkerton AB, Bottini N. Stanford SM, et al. Among authors: liddington rc. Nat Chem Biol. 2017 Jun;13(6):624-632. doi: 10.1038/nchembio.2344. Epub 2017 Mar 27. Nat Chem Biol. 2017. PMID: 28346406 Free PMC article.
148 results