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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: de jong pr. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.
MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance.
Lee B, Sahoo A, Sawada J, Marchica J, Sahoo S, Layng FIAL, Finlay D, Mazar J, Joshi P, Komatsu M, Vuori K, de Jong PR, Ray A, Perera RJ. Lee B, et al. Among authors: de jong pr. J Invest Dermatol. 2021 Feb;141(2):385-394. doi: 10.1016/j.jid.2020.06.038. Epub 2020 Sep 2. J Invest Dermatol. 2021. PMID: 32888955 Free PMC article.
YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Taniguchi K, Moroishi T, de Jong PR, Krawczyk M, Grebbin BM, Luo H, Xu RH, Golob-Schwarzl N, Schweiger C, Wang K, Di Caro G, Feng Y, Fearon ER, Raz E, Kenner L, Farin HF, Guan KL, Haybaeck J, Datz C, Zhang K, Karin M. Taniguchi K, et al. Among authors: de jong pr. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1643-1648. doi: 10.1073/pnas.1620290114. Epub 2017 Jan 27. Proc Natl Acad Sci U S A. 2017. PMID: 28130546 Free PMC article.
Novel immune function for the TRPV1 channel in T lymphocytes.
Bertin S, de Jong PR, Jefferies WA, Raz E. Bertin S, et al. Among authors: de jong pr. Channels (Austin). 2014;8(6):479-80. doi: 10.4161/19336950.2014.991640. Channels (Austin). 2014. PMID: 25530461 Free PMC article. No abstract available.
TRPV1: Turning up the heat on intestinal tumorigenesis.
de Jong PR, Bertin S, Raz E. de Jong PR, et al. Mol Cell Oncol. 2014 Dec 1;2(1):e975619. doi: 10.4161/23723556.2014.975619. eCollection 2015 Jan-Mar. Mol Cell Oncol. 2014. PMID: 27308393 Free PMC article.
STAT3: An Anti-Invasive Factor in Colorectal Cancer?
de Jong PR, Mo JH, Harris AR, Lee J, Raz E. de Jong PR, et al. Cancers (Basel). 2014 Jul 3;6(3):1394-407. doi: 10.3390/cancers6031394. Cancers (Basel). 2014. PMID: 24995503 Free PMC article.
A gp130-Src-YAP module links inflammation to epithelial regeneration.
Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Zucman-Rossi J, Guan KL, Karin M. Taniguchi K, et al. Among authors: de jong pr. Nature. 2015 Mar 5;519(7541):57-62. doi: 10.1038/nature14228. Epub 2015 Feb 25. Nature. 2015. PMID: 25731159 Free PMC article.
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