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Page 1
Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling.
Brunen D, García-Barchino MJ, Malani D, Jagalur Basheer N, Lieftink C, Beijersbergen RL, Murumägi A, Porkka K, Wolf M, Zwaan CM, Fornerod M, Kallioniemi O, Martínez-Climent JÁ, Bernards R. Brunen D, et al. Among authors: fornerod m. Oncotarget. 2016 Jun 21;7(25):37407-37419. doi: 10.18632/oncotarget.9822. Oncotarget. 2016. PMID: 27270648 Free PMC article.
miR-9 is a tumor suppressor in pediatric AML with t(8;21).
Emmrich S, Katsman-Kuipers JE, Henke K, Khatib ME, Jammal R, Engeland F, Dasci F, Zwaan CM, den Boer ML, Verboon L, Stary J, Baruchel A, de Haas V, Danen-van Oorschot AA, Fornerod M, Pieters R, Reinhardt D, Klusmann JH, van den Heuvel-Eibrink MM. Emmrich S, et al. Among authors: fornerod m. Leukemia. 2014 May;28(5):1022-32. doi: 10.1038/leu.2013.357. Epub 2013 Nov 25. Leukemia. 2014. PMID: 24270738
BCOR and BCORL1 mutations in pediatric acute myeloid leukemia.
de Rooij JD, van den Heuvel-Eibrink MM, Hermkens MC, Verboon LJ, Arentsen-Peters ST, Fornerod M, Baruchel A, Stary J, Reinhardt D, de Haas V, Pieters R, Zwaan CM. de Rooij JD, et al. Among authors: fornerod m. Haematologica. 2015 May;100(5):e194-5. doi: 10.3324/haematol.2014.117796. Epub 2015 Jan 16. Haematologica. 2015. PMID: 25596268 Free PMC article. No abstract available.
Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia.
de Rooij JD, Beuling E, van den Heuvel-Eibrink MM, Obulkasim A, Baruchel A, Trka J, Reinhardt D, Sonneveld E, Gibson BE, Pieters R, Zimmermann M, Zwaan CM, Fornerod M. de Rooij JD, et al. Among authors: fornerod m. Haematologica. 2015 Sep;100(9):1151-9. doi: 10.3324/haematol.2015.124321. Epub 2015 Jun 11. Haematologica. 2015. PMID: 26069293 Free PMC article. Clinical Trial.
Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study.
de Rooij JD, Masetti R, van den Heuvel-Eibrink MM, Cayuela JM, Trka J, Reinhardt D, Rasche M, Sonneveld E, Alonzo TA, Fornerod M, Zimmermann M, Pigazzi M, Pieters R, Meshinchi S, Zwaan CM, Locatelli F. de Rooij JD, et al. Among authors: fornerod m. Blood. 2016 Jun 30;127(26):3424-30. doi: 10.1182/blood-2016-01-695551. Epub 2016 Apr 25. Blood. 2016. PMID: 27114462 Free PMC article.
MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia.
Verboon LJ, Obulkasim A, de Rooij JD, Katsman-Kuipers JE, Sonneveld E, Baruchel A, Trka J, Reinhardt D, Pieters R, Cloos J, Kaspers GJ, Klusmann JH, Zwaan CM, Fornerod M, van den Heuvel-Eibrink MM. Verboon LJ, et al. Among authors: fornerod m. Oncotarget. 2016 Jul 26;7(30):48412-48422. doi: 10.18632/oncotarget.10270. Oncotarget. 2016. PMID: 27351222 Free PMC article.
PHF6 mutations in paediatric acute myeloid leukaemia.
de Rooij JD, van den Heuvel-Eibrink MM, van de Rijdt NK, Verboon LJ, de Haas V, Trka J, Baruchel A, Reinhardt D, Pieters R, Fornerod M, Zwaan CM. de Rooij JD, et al. Among authors: fornerod m. Br J Haematol. 2016 Dec;175(5):967-971. doi: 10.1111/bjh.13891. Epub 2015 Dec 21. Br J Haematol. 2016. PMID: 27885656 Free article. No abstract available.
Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
de Rooij JD, Branstetter C, Ma J, Li Y, Walsh MP, Cheng J, Obulkasim A, Dang J, Easton J, Verboon LJ, Mulder HL, Zimmermann M, Koss C, Gupta P, Edmonson M, Rusch M, Lim JY, Reinhardt K, Pigazzi M, Song G, Yeoh AE, Shih LY, Liang DC, Halene S, Krause DS, Zhang J, Downing JR, Locatelli F, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M, Gruber TA. de Rooij JD, et al. Among authors: fornerod m. Nat Genet. 2017 Mar;49(3):451-456. doi: 10.1038/ng.3772. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112737 Free PMC article.
Classification of pediatric acute myeloid leukemia based on miRNA expression profiles.
Obulkasim A, Katsman-Kuipers JE, Verboon L, Sanders M, Touw I, Jongen-Lavrencic M, Pieters R, Klusmann JH, Michel Zwaan C, van den Heuvel-Eibrink MM, Fornerod M. Obulkasim A, et al. Among authors: fornerod m. Oncotarget. 2017 May 16;8(20):33078-33085. doi: 10.18632/oncotarget.16525. Oncotarget. 2017. PMID: 28380436 Free PMC article.
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