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The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.
Rambout X, Detiffe C, Bruyr J, Mariavelle E, Cherkaoui M, Brohée S, Demoitié P, Lebrun M, Soin R, Lesage B, Guedri K, Beullens M, Bollen M, Farazi TA, Kettmann R, Struman I, Hill DE, Vidal M, Kruys V, Simonis N, Twizere JC, Dequiedt F. Rambout X, et al. Among authors: brohee s. Nat Struct Mol Biol. 2016 Jul;23(7):663-72. doi: 10.1038/nsmb.3243. Epub 2016 Jun 6. Nat Struct Mol Biol. 2016. PMID: 27273514 Free article.
SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
Boumahdi S, Driessens G, Lapouge G, Rorive S, Nassar D, Le Mercier M, Delatte B, Caauwe A, Lenglez S, Nkusi E, Brohée S, Salmon I, Dubois C, del Marmol V, Fuks F, Beck B, Blanpain C. Boumahdi S, et al. Among authors: brohee s. Nature. 2014 Jul 10;511(7508):246-50. doi: 10.1038/nature13305. Epub 2014 Jun 8. Nature. 2014. PMID: 24909994
Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity.
Van Keymeulen A, Lee MY, Ousset M, Brohée S, Rorive S, Giraddi RR, Wuidart A, Bouvencourt G, Dubois C, Salmon I, Sotiriou C, Phillips WA, Blanpain C. Van Keymeulen A, et al. Among authors: brohee s. Nature. 2015 Sep 3;525(7567):119-23. doi: 10.1038/nature14665. Epub 2015 Aug 12. Nature. 2015. PMID: 26266985
Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation.
Youssef KK, Lapouge G, Bouvrée K, Rorive S, Brohée S, Appelstein O, Larsimont JC, Sukumaran V, Van de Sande B, Pucci D, Dekoninck S, Berthe JV, Aerts S, Salmon I, del Marmol V, Blanpain C. Youssef KK, et al. Among authors: brohee s. Nat Cell Biol. 2012 Dec;14(12):1282-94. doi: 10.1038/ncb2628. Epub 2012 Nov 25. Nat Cell Biol. 2012. PMID: 23178882
Biology of breast cancer during pregnancy using genomic profiling.
Azim HA Jr, Brohée S, Peccatori FA, Desmedt C, Loi S, Lambrechts D, Dell'Orto P, Majjaj S, Jose V, Rotmensz N, Ignatiadis M, Pruneri G, Piccart M, Viale G, Sotiriou C. Azim HA Jr, et al. Among authors: brohee s. Endocr Relat Cancer. 2014 Aug;21(4):545-54. doi: 10.1530/ERC-14-0111. Epub 2014 May 13. Endocr Relat Cancer. 2014. PMID: 24825746
Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.
Berns K, Sonnenblick A, Gennissen A, Brohée S, Hijmans EM, Evers B, Fumagalli D, Desmedt C, Loibl S, Denkert C, Neven P, Guo W, Zhang F, Knijnenburg TA, Bosse T, van der Heijden MS, Hindriksen S, Nijkamp W, Wessels LF, Joensuu H, Mills GB, Beijersbergen RL, Sotiriou C, Bernards R. Berns K, et al. Among authors: brohee s. Clin Cancer Res. 2016 Nov 1;22(21):5238-5248. doi: 10.1158/1078-0432.CCR-15-2996. Epub 2016 May 12. Clin Cancer Res. 2016. PMID: 27172896
The footprint of the ageing stroma in older patients with breast cancer.
Brouwers B, Fumagalli D, Brohee S, Hatse S, Govaere O, Floris G, Van den Eynde K, Bareche Y, Schöffski P, Smeets A, Neven P, Lambrechts D, Sotiriou C, Wildiers H. Brouwers B, et al. Among authors: brohee s. Breast Cancer Res. 2017 Jul 3;19(1):78. doi: 10.1186/s13058-017-0871-0. Breast Cancer Res. 2017. PMID: 28673354 Free PMC article.
39 results