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Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.
Kelkka T, Kienhöfer D, Hoffmann M, Linja M, Wing K, Sareila O, Hultqvist M, Laajala E, Chen Z, Vasconcelos J, Neves E, Guedes M, Marques L, Krönke G, Helminen M, Kainulainen L, Olofsson P, Jalkanen S, Lahesmaa R, Souto-Carneiro MM, Holmdahl R. Kelkka T, et al. Among authors: kienhofer d. Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29. Antioxid Redox Signal. 2014. PMID: 24787605 Free PMC article.
Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.
Kienhöfer D, Hahn J, Stoof J, Csepregi JZ, Reinwald C, Urbonaviciute V, Johnsson C, Maueröder C, Podolska MJ, Biermann MH, Leppkes M, Harrer T, Hultqvist M, Olofsson P, Munoz LE, Mocsai A, Herrmann M, Schett G, Holmdahl R, Hoffmann MH. Kienhöfer D, et al. JCI Insight. 2017 May 18;2(10):e92920. doi: 10.1172/jci.insight.92920. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515366 Free PMC article.
NOX2 mediates quiescent handling of dead cell remnants in phagocytes.
Hahn J, Euler M, Kilgus E, Kienhöfer D, Stoof J, Knopf J, Hahn M, Harrer T, Hultqvist M, Olofsson P, Mokhir A, Holmdahl R, Herrmann M, Schett G, Muñoz LE, Hoffmann MH. Hahn J, et al. Among authors: kienhofer d. Redox Biol. 2019 Sep;26:101279. doi: 10.1016/j.redox.2019.101279. Epub 2019 Jul 20. Redox Biol. 2019. PMID: 31349119 Free PMC article.
19 results