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TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression.
Bjerre C, Vinther L, Belling KC, Würtz SØ, Yadav R, Lademann U, Rigina O, Do KN, Ditzel HJ, Lykkesfeldt AE, Wang J, Nielsen HB, Brünner N, Gupta R, Schrohl AS, Stenvang J. Bjerre C, et al. Among authors: ditzel hj. Tumour Biol. 2013 Dec;34(6):3839-51. doi: 10.1007/s13277-013-0969-7. Epub 2013 Jul 24. Tumour Biol. 2013. PMID: 23881388
Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties.
Lin X, Li J, Yin G, Zhao Q, Elias D, Lykkesfeldt AE, Stenvang J, Brünner N, Wang J, Yang H, Bolund L, Ditzel HJ. Lin X, et al. Among authors: ditzel hj. Breast Cancer Res. 2013 Dec 19;15(6):R119. doi: 10.1186/bcr3588. Breast Cancer Res. 2013. PMID: 24355041 Free PMC article.
Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways.
Hansen SN, Westergaard D, Thomsen MB, Vistesen M, Do KN, Fogh L, Belling KC, Wang J, Yang H, Gupta R, Ditzel HJ, Moreira J, Brünner N, Stenvang J, Schrohl AS. Hansen SN, et al. Among authors: ditzel hj. Tumour Biol. 2015 Jun;36(6):4327-38. doi: 10.1007/s13277-015-3072-4. Epub 2015 Jan 18. Tumour Biol. 2015. PMID: 25596703
209 results