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Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment.
Kordasti S, Costantini B, Seidl T, Perez Abellan P, Martinez Llordella M, McLornan D, Diggins KE, Kulasekararaj A, Benfatto C, Feng X, Smith A, Mian SA, Melchiotti R, de Rinaldis E, Ellis R, Petrov N, Povoleri GA, Chung SS, Thomas NS, Farzaneh F, Irish JM, Heck S, Young NS, Marsh JC, Mufti GJ. Kordasti S, et al. Among authors: martinez llordella m. Blood. 2016 Sep 1;128(9):1193-205. doi: 10.1182/blood-2016-03-703702. Epub 2016 Jun 8. Blood. 2016. PMID: 27281795 Free PMC article. Clinical Trial.
Impact of liver failure on the circulating extracellular vesicle miRNA repertoire.
Mastoridis S, Patel V, Christakoudi S, Lozano JJ, Salehi S, Kurt A, Grossart C, Kodela E, Martinez-Llordella M, Sanchez-Fueyo A. Mastoridis S, et al. Among authors: martinez llordella m. Hepatol Res. 2023 Aug;53(8):771-785. doi: 10.1111/hepr.13909. Epub 2023 May 2. Hepatol Res. 2023. PMID: 37060575
Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation.
Sánchez-Fueyo A, Whitehouse G, Grageda N, Cramp ME, Lim TY, Romano M, Thirkell S, Lowe K, Fry L, Heward J, Kerr A, Ali J, Fisher C, Lewis G, Hope A, Kodela E, Lyne M, Farzaneh F, Kordasti S, Rebollo-Mesa I, Jose Lozano J, Safinia N, Heaton N, Lechler R, Martínez-Llordella M, Lombardi G. Sánchez-Fueyo A, et al. Among authors: martinez llordella m. Am J Transplant. 2020 Apr;20(4):1125-1136. doi: 10.1111/ajt.15700. Epub 2020 Feb 3. Am J Transplant. 2020. PMID: 31715056 Free PMC article. Clinical Trial.
Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction.
Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ. Lim SP, et al. Among authors: martinez llordella m. Blood. 2020 Aug 13;136(7):885-897. doi: 10.1182/blood.2019001347. Blood. 2020. PMID: 32294156 Free PMC article.
IL-2 availability regulates the tissue specific phenotype of murine intra-hepatic Tregs.
Kurt AS, Strobl K, Ruiz P, Osborn G, Chester T, Dawson L, Warwas KM, Grey EH, Mastoridis S, Kodela E, Safinia N, Sanchez-Fueyo A, Martinez-Llordella M. Kurt AS, et al. Among authors: martinez llordella m. Front Immunol. 2022 Oct 31;13:1040031. doi: 10.3389/fimmu.2022.1040031. eCollection 2022. Front Immunol. 2022. PMID: 36389734 Free PMC article.
In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression.
Liberal R, Grant CR, Holder BS, Cardone J, Martinez-Llordella M, Ma Y, Heneghan MA, Mieli-Vergani G, Vergani D, Longhi MS. Liberal R, et al. Among authors: martinez llordella m. Hepatology. 2015 Sep;62(3):863-75. doi: 10.1002/hep.27884. Epub 2015 Jun 18. Hepatology. 2015. PMID: 25953611 Free article.
IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors.
Whitehouse G, Gray E, Mastoridis S, Merritt E, Kodela E, Yang JHM, Danger R, Mairal M, Christakoudi S, Lozano JJ, Macdougall IC, Tree TIM, Sanchez-Fueyo A, Martinez-Llordella M. Whitehouse G, et al. Among authors: martinez llordella m. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7083-7088. doi: 10.1073/pnas.1620835114. Epub 2017 Jun 5. Proc Natl Acad Sci U S A. 2017. PMID: 28584086 Free PMC article.
Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response.
Bonaccorsi-Riani E, Danger R, Lozano JJ, Martinez-Picola M, Kodela E, Mas-Malavila R, Bruguera M, Collins HL, Hider RC, Martinez-Llordella M, Sanchez-Fueyo A. Bonaccorsi-Riani E, et al. Among authors: martinez llordella m, martinez picola m. PLoS One. 2015 Aug 19;10(8):e0136106. doi: 10.1371/journal.pone.0136106. eCollection 2015. PLoS One. 2015. PMID: 26287688 Free PMC article.
45 results