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BSR and BHPR guideline for the treatment of systemic sclerosis.
Denton CP, Hughes M, Gak N, Vila J, Buch MH, Chakravarty K, Fligelstone K, Gompels LL, Griffiths B, Herrick AL, Pang J, Parker L, Redmond A, van Laar J, Warburton L, Ong VH; BSR and BHPR Standards, Guidelines and Audit Working Group. Denton CP, et al. Rheumatology (Oxford). 2016 Oct;55(10):1906-10. doi: 10.1093/rheumatology/kew224. Epub 2016 Jun 9. Rheumatology (Oxford). 2016. PMID: 27284161 Free article. Review. No abstract available.
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.
Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B. Denton CP, et al. J Biol Chem. 2003 Jul 4;278(27):25109-19. doi: 10.1074/jbc.M300636200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707256 Free article.
Pulmonary hypertension in systemic sclerosis.
Denton CP, Black CM. Denton CP, et al. Rheum Dis Clin North Am. 2003 May;29(2):335-49, vii. doi: 10.1016/s0889-857x(03)00024-3. Rheum Dis Clin North Am. 2003. PMID: 12841298 Review.
Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k).
Denton CP, Lindahl GE, Khan K, Shiwen X, Ong VH, Gaspar NJ, Lazaridis K, Edwards DR, Leask A, Eastwood M, Leoni P, Renzoni EA, Bou Gharios G, Abraham DJ, Black CM. Denton CP, et al. J Biol Chem. 2005 Apr 22;280(16):16053-65. doi: 10.1074/jbc.M413134200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15708853 Free article.
Management of systemic sclerosis.
Ong VH, Brough G, Denton CP. Ong VH, et al. Among authors: denton cp. Clin Med (Lond). 2005 May-Jun;5(3):214-9. doi: 10.7861/clinmedicine.5-3-214. Clin Med (Lond). 2005. PMID: 16011210 Free PMC article. Review. No abstract available.
A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma.
Hoyles RK, Ellis RW, Wellsbury J, Lees B, Newlands P, Goh NS, Roberts C, Desai S, Herrick AL, McHugh NJ, Foley NM, Pearson SB, Emery P, Veale DJ, Denton CP, Wells AU, Black CM, du Bois RM. Hoyles RK, et al. Among authors: denton cp. Arthritis Rheum. 2006 Dec;54(12):3962-70. doi: 10.1002/art.22204. Arthritis Rheum. 2006. PMID: 17133610 Free article. Clinical Trial.
Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192.
Denton CP, Merkel PA, Furst DE, Khanna D, Emery P, Hsu VM, Silliman N, Streisand J, Powell J, Akesson A, Coppock J, Hoogen Fv, Herrick A, Mayes MD, Veale D, Haas J, Ledbetter S, Korn JH, Black CM, Seibold JR; Cat-192 Study Group; Scleroderma Clinical Trials Consortium. Denton CP, et al. Arthritis Rheum. 2007 Jan;56(1):323-33. doi: 10.1002/art.22289. Arthritis Rheum. 2007. PMID: 17195236 Free article. Clinical Trial.
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