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Baeyer-Villiger Monooxygenases EthA and MymA Are Required for Activation of Replicating and Non-replicating Mycobacterium tuberculosis Inhibitors.
Cell Chem Biol. 2016 Jun 23;23(6):666-77. doi: 10.1016/j.chembiol.2016.05.011. Epub 2016 Jun 16.
Cell Chem Biol. 2016.
PMID: 27321573
Free PMC article.
Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.
Stanley SA, Grant SS, Kawate T, Iwase N, Shimizu M, Wivagg C, Silvis M, Kazyanskaya E, Aquadro J, Golas A, Fitzgerald M, Dai H, Zhang L, Hung DT.
Stanley SA, et al. Among authors: kazyanskaya e.
ACS Chem Biol. 2012 Aug 17;7(8):1377-84. doi: 10.1021/cb300151m. Epub 2012 May 21.
ACS Chem Biol. 2012.
PMID: 22577943
Free PMC article.
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Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model.
Grant SS, Kawate T, Nag PP, Silvis MR, Gordon K, Stanley SA, Kazyanskaya E, Nietupski R, Golas A, Fitzgerald M, Cho S, Franzblau SG, Hung DT.
Grant SS, et al. Among authors: kazyanskaya e.
ACS Chem Biol. 2013 Oct 18;8(10):2224-34. doi: 10.1021/cb4004817. Epub 2013 Aug 13.
ACS Chem Biol. 2013.
PMID: 23898841
Free PMC article.
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Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
Stanley SA, Kawate T, Iwase N, Shimizu M, Clatworthy AE, Kazyanskaya E, Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S, Aquadro JA, Grant SS, Rubin EJ, Hung DT.
Stanley SA, et al. Among authors: kazyanskaya e.
Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11565-70. doi: 10.1073/pnas.1302114110. Epub 2013 Jun 24.
Proc Natl Acad Sci U S A. 2013.
PMID: 23798446
Free PMC article.
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Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.
Kawate T, Iwase N, Shimizu M, Stanley SA, Wellington S, Kazyanskaya E, Hung DT.
Kawate T, et al. Among authors: kazyanskaya e.
Bioorg Med Chem Lett. 2013 Nov 15;23(22):6052-9. doi: 10.1016/j.bmcl.2013.09.035. Epub 2013 Sep 19.
Bioorg Med Chem Lett. 2013.
PMID: 24103299
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The first synthesis of an epidiselenodiketopiperazine.
McMahon TC, Stanley S, Kazyanskaya E, Hung D, Wood JL.
McMahon TC, et al. Among authors: kazyanskaya e.
Org Lett. 2012 Sep 7;14(17):4534-6. doi: 10.1021/ol3020094. Epub 2012 Aug 22.
Org Lett. 2012.
PMID: 22913407
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