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Microglia development follows a stepwise program to regulate brain homeostasis.
Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I. Matcovitch-Natan O, et al. Among authors: vargas aguilar s. Science. 2016 Aug 19;353(6301):aad8670. doi: 10.1126/science.aad8670. Epub 2016 Jun 23. Science. 2016. PMID: 27338705
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian S, Busch CJ, Molawi K, Geirsdottir L, Maurizio J, Vargas Aguilar S, Belahbib H, Gimenez G, Yuda RAA, Burkon M, Favret J, Gholamhosseinian Najjar S, de Laval B, Kandalla PK, Sarrazin S, Alexopoulou L, Sieweke MH. Subramanian S, et al. Among authors: vargas aguilar s. Nat Immunol. 2022 Mar;23(3):458-468. doi: 10.1038/s41590-022-01146-w. Epub 2022 Feb 24. Nat Immunol. 2022. PMID: 35210623
SIRT1 regulates macrophage self-renewal.
Imperatore F, Maurizio J, Vargas Aguilar S, Busch CJ, Favret J, Kowenz-Leutz E, Cathou W, Gentek R, Perrin P, Leutz A, Berruyer C, Sieweke MH. Imperatore F, et al. Among authors: vargas aguilar s. EMBO J. 2017 Aug 15;36(16):2353-2372. doi: 10.15252/embj.201695737. Epub 2017 Jul 12. EMBO J. 2017. PMID: 28701484 Free PMC article.