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Neddylation requires glycyl-tRNA synthetase to protect activated E2.
Mo Z, Zhang Q, Liu Z, Lauer J, Shi Y, Sun L, Griffin PR, Yang XL. Mo Z, et al. Among authors: griffin pr. Nat Struct Mol Biol. 2016 Aug;23(8):730-7. doi: 10.1038/nsmb.3250. Epub 2016 Jun 27. Nat Struct Mol Biol. 2016. PMID: 27348078 Free PMC article.
DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.
Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Wang Y, Busby SA, Pascal BD, Garcia-Ordonez RD, Bruning JB, Istrate MA, Kojetin DJ, Dodge JA, Burris TP, Griffin PR. Zhang J, et al. Among authors: griffin pr. Nat Struct Mol Biol. 2011 May;18(5):556-63. doi: 10.1038/nsmb.2046. Epub 2011 Apr 10. Nat Struct Mol Biol. 2011. PMID: 21478866 Free PMC article.
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.
Solt LA, Kumar N, Nuhant P, Wang Y, Lauer JL, Liu J, Istrate MA, Kamenecka TM, Roush WR, Vidović D, Schürer SC, Xu J, Wagoner G, Drew PD, Griffin PR, Burris TP. Solt LA, et al. Among authors: griffin pr. Nature. 2011 Apr 28;472(7344):491-4. doi: 10.1038/nature10075. Epub 2011 Apr 17. Nature. 2011. PMID: 21499262 Free PMC article.
HDX workbench: software for the analysis of H/D exchange MS data.
Pascal BD, Willis S, Lauer JL, Landgraf RR, West GM, Marciano D, Novick S, Goswami D, Chalmers MJ, Griffin PR. Pascal BD, et al. Among authors: griffin pr. J Am Soc Mass Spectrom. 2012 Sep;23(9):1512-21. doi: 10.1007/s13361-012-0419-6. Epub 2012 Jun 13. J Am Soc Mass Spectrom. 2012. PMID: 22692830 Free PMC article.
CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.
He W, Bai G, Zhou H, Wei N, White NM, Lauer J, Liu H, Shi Y, Dumitru CD, Lettieri K, Shubayev V, Jordanova A, Guergueltcheva V, Griffin PR, Burgess RW, Pfaff SL, Yang XL. He W, et al. Among authors: griffin pr. Nature. 2015 Oct 29;526(7575):710-4. doi: 10.1038/nature15510. Epub 2015 Oct 21. Nature. 2015. PMID: 26503042 Free PMC article.
CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS.
Sun L, Wei N, Kuhle B, Blocquel D, Novick S, Matuszek Z, Zhou H, He W, Zhang J, Weber T, Horvath R, Latour P, Pan T, Schimmel P, Griffin PR, Yang XL. Sun L, et al. Among authors: griffin pr. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2012898118. doi: 10.1073/pnas.2012898118. Proc Natl Acad Sci U S A. 2021. PMID: 33753480 Free PMC article.
Identification of SR2211: a potent synthetic RORγ-selective modulator.
Kumar N, Lyda B, Chang MR, Lauer JL, Solt LA, Burris TP, Kamenecka TM, Griffin PR. Kumar N, et al. Among authors: griffin pr. ACS Chem Biol. 2012 Apr 20;7(4):672-7. doi: 10.1021/cb200496y. Epub 2012 Feb 13. ACS Chem Biol. 2012. PMID: 22292739 Free PMC article.
280 results