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Determination of unbound vismodegib (GDC-0449) concentration in human plasma using rapid equilibrium dialysis followed by solid phase extraction and high-performance liquid chromatography coupled to mass spectrometry.
Deng Y, Wong H, Graham RA, Liu W, Shen HS, Shi Y, Wang L, Meng M, Malhi V, Ding X, Dean B. Deng Y, et al. Among authors: dean b. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2119-26. doi: 10.1016/j.jchromb.2011.05.048. Epub 2011 Jun 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21704573
A solid phase extraction-liquid chromatographic-tandem mass spectrometry method for determination of concentrations of GDC-0941, a small molecule class I phosphatidylinositide 3-kinase inhibitor, to support clinical development.
Ding X, Morrison G, Dean B, Hop CE, Tobler L, Percey S, Meng M, Reuschel S, West DA, Holden S, Ware JA. Ding X, et al. Among authors: dean b. J Pharm Biomed Anal. 2012 Mar 5;61:1-7. doi: 10.1016/j.jpba.2011.11.005. Epub 2011 Nov 25. J Pharm Biomed Anal. 2012. PMID: 22169467 Clinical Trial.
Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of G-856 (Cur-61414) in human plasma using semi-automated solid phase extraction.
Shin YG, Murakami SC, Buonarati MH, Dean B, Hop CE. Shin YG, et al. Among authors: dean b. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 1;887-888:85-92. doi: 10.1016/j.jchromb.2012.01.016. Epub 2012 Jan 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22317788
Surrogate analyte approach for quantitation of endogenous NAD(+) in human acidified blood samples using liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Liu L, Cui Z, Deng Y, Dean B, Hop CE, Liang X. Liu L, et al. Among authors: dean b. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 1;1011:69-76. doi: 10.1016/j.jchromb.2015.12.040. Epub 2015 Dec 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26766786
918 results