Goodenough A - Search Results

1

Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity.

Aubry AF, Dean B, Diczfalusy U, Goodenough A, Iffland A, McLeod J, Weng N, Yang Z. Aubry AF, et al. Among authors: goodenough a. AAPS J. 2016 Sep;18(5):1056-1066. doi: 10.1208/s12248-016-9949-3. Epub 2016 Jun 27. AAPS J. 2016. PMID: 27350147 Review.

2

Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects.

Kasichayanula S, Boulton DW, Luo WL, Rodrigues AD, Yang Z, Goodenough A, Lee M, Jemal M, LaCreta F. Kasichayanula S, et al. Among authors: goodenough a. Br J Clin Pharmacol. 2014 Nov;78(5):1122-34. doi: 10.1111/bcp.12425. Br J Clin Pharmacol. 2014. PMID: 24837659 Free PMC article. Clinical Trial.

3

Quantification of 4-beta-hydroxycholesterol in human plasma using automated sample preparation and LC-ESI-MS/MS analysis.

Goodenough AK, Onorato JM, Ouyang Z, Chang S, Rodrigues AD, Kasichayanula S, Huang SP, Turley W, Burrell R, Bifano M, Jemal M, LaCreta F, Tymiak A, Wang-Iverson D. Goodenough AK, et al. Chem Res Toxicol. 2011 Sep 19;24(9):1575-85. doi: 10.1021/tx2001898. Epub 2011 Jul 21. Chem Res Toxicol. 2011. PMID: 21728364

4

Characterization of protein therapeutics by mass spectrometry: recent developments and future directions.

Chen G, Warrack BM, Goodenough AK, Wei H, Wang-Iverson DB, Tymiak AA. Chen G, et al. Among authors: goodenough ak. Drug Discov Today. 2011 Jan;16(1-2):58-64. doi: 10.1016/j.drudis.2010.11.003. Epub 2010 Nov 18. Drug Discov Today. 2011. PMID: 21093608 Review.

5

Novel LC-ESI/MS/MS(n) method for the characterization and quantification of 2'-deoxyguanosine adducts of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by 2-D linear quadrupole ion trap mass spectrometry.

Goodenough AK, Schut HA, Turesky RJ. Goodenough AK, et al. Chem Res Toxicol. 2007 Feb;20(2):263-76. doi: 10.1021/tx0601713. Chem Res Toxicol. 2007. PMID: 17305409 Free PMC article.

6

Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.

Bessette EE, Spivack SD, Goodenough AK, Wang T, Pinto S, Kadlubar FF, Turesky RJ. Bessette EE, et al. Chem Res Toxicol. 2010 Jul 19;23(7):1234-44. doi: 10.1021/tx100098f. Chem Res Toxicol. 2010. PMID: 20443584 Free PMC article.

7

Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.

Huang A, Jayaraman L, Fura A, Vite GD, Trainor GL, Gottardis MM, Spires TE, Spires VM, Rizzo CA, Obermeier MT, Elzinga PA, Todderud G, Fan Y, Newitt JA, Beyer SM, Zhu Y, Warrack BM, Goodenough AK, Tebben AJ, Doweyko AM, Gold DL, Balog A. Huang A, et al. Among authors: goodenough ak. ACS Med Chem Lett. 2015 Dec 2;7(1):40-5. doi: 10.1021/acsmedchemlett.5b00310. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819663 Free PMC article.

8

Identification of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline: an abundant mutagenic heterocyclic aromatic amine formed in cooked beef.

Turesky RJ, Goodenough AK, Ni W, McNaughton L, LeMaster DM, Holland RD, Wu RW, Felton JS. Turesky RJ, et al. Chem Res Toxicol. 2007 Mar;20(3):520-30. doi: 10.1021/tx600317r. Epub 2007 Feb 23. Chem Res Toxicol. 2007. PMID: 17316027 Free PMC article.

9

Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.

Goodenough AK, Kozekov ID, Zang H, Choi JY, Guengerich FP, Harris TM, Rizzo CJ. Goodenough AK, et al. Chem Res Toxicol. 2005 Nov;18(11):1701-14. doi: 10.1021/tx050141k. Chem Res Toxicol. 2005. PMID: 16300379 Free PMC article.

10

Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells.

Spink BC, Bennett JA, Pentecost BT, Lostritto N, Englert NA, Benn GK, Goodenough AK, Turesky RJ, Spink DC. Spink BC, et al. Among authors: goodenough ak. Toxicol Appl Pharmacol. 2009 Nov 1;240(3):355-66. doi: 10.1016/j.taap.2009.07.013. Epub 2009 Jul 18. Toxicol Appl Pharmacol. 2009. PMID: 19619570 Free PMC article.

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