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Supramolecular Control over Split-Luciferase Complementation.
Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8899-903. doi: 10.1002/anie.201602807. Epub 2016 Jun 29.
Angew Chem Int Ed Engl. 2016.
PMID: 27356091
Free PMC article.
A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.
de Vink PJ, Briels JM, Schrader T, Milroy LG, Brunsveld L, Ottmann C.
de Vink PJ, et al. Among authors: briels jm.
Angew Chem Int Ed Engl. 2017 Jul 24;56(31):8998-9002. doi: 10.1002/anie.201701807. Epub 2017 Jun 29.
Angew Chem Int Ed Engl. 2017.
PMID: 28510303
Free PMC article.
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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
Bier D, Mittal S, Bravo-Rodriguez K, Sowislok A, Guillory X, Briels J, Heid C, Bartel M, Wettig B, Brunsveld L, Sanchez-Garcia E, Schrader T, Ottmann C.
Bier D, et al.
J Am Chem Soc. 2017 Nov 15;139(45):16256-16263. doi: 10.1021/jacs.7b07939. Epub 2017 Nov 2.
J Am Chem Soc. 2017.
PMID: 29039919
Free PMC article.
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Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Yilmaz E, Bier D, Guillory X, Briels J, Ruiz-Blanco YB, Sanchez-Garcia E, Ottmann C, Kaiser M.
Yilmaz E, et al.
Chemistry. 2018 Sep 18;24(52):13807-13814. doi: 10.1002/chem.201801074. Epub 2018 Aug 22.
Chemistry. 2018.
PMID: 29924885
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Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter Protein.
Ehlers M, Grad JN, Mittal S, Bier D, Mertel M, Ohl L, Bartel M, Briels J, Heimann M, Ottmann C, Sanchez-Garcia E, Hoffmann D, Schmuck C.
Ehlers M, et al.
Chembiochem. 2018 Mar 16;19(6):591-595. doi: 10.1002/cbic.201700588. Epub 2018 Feb 15.
Chembiochem. 2018.
PMID: 29282826
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Stabilization of Protein-Protein Interactions in chemical biology and drug discovery.
Bier D, Thiel P, Briels J, Ottmann C.
Bier D, et al.
Prog Biophys Mol Biol. 2015 Oct;119(1):10-9. doi: 10.1016/j.pbiomolbio.2015.05.002. Epub 2015 Jun 18.
Prog Biophys Mol Biol. 2015.
PMID: 26093250
Review.
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A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude.
Gigante A , Grad JN , Briels J , Bartel M , Hoffmann D , Ottmann C , Schmuck C .
Gigante A , et al.
Chem Commun (Camb). 2018 Dec 18;55(1):111-114. doi: 10.1039/c8cc07946c.
Chem Commun (Camb). 2018.
PMID: 30515494
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Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein-Protein Interactions.
Bartsch L, Bartel M, Gigante A, Iglesias-Fernández J, Ruiz-Blanco YB, Beuck C, Briels J, Toetsch N, Bayer P, Sanchez-Garcia E, Ottmann C, Schmuck C.
Bartsch L, et al.
Chembiochem. 2019 Dec 2;20(23):2921-2926. doi: 10.1002/cbic.201900288. Epub 2019 Sep 24.
Chembiochem. 2019.
PMID: 31168888
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