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Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.
Ghisi M, Kats L, Masson F, Li J, Kratina T, Vidacs E, Gilan O, Doyle MA, Newbold A, Bolden JE, Fairfax KA, de Graaf CA, Firth M, Zuber J, Dickins RA, Corcoran LM, Dawson MA, Belz GT, Johnstone RW. Ghisi M, et al. Among authors: newbold a. Cancer Cell. 2016 Jul 11;30(1):59-74. doi: 10.1016/j.ccell.2016.05.019. Epub 2016 Jun 30. Cancer Cell. 2016. PMID: 27374225 Free article.
A central role for Bid in granzyme B-induced apoptosis.
Waterhouse NJ, Sedelies KA, Browne KA, Wowk ME, Newbold A, Sutton VR, Clarke CJ, Oliaro J, Lindemann RK, Bird PI, Johnstone RW, Trapani JA. Waterhouse NJ, et al. Among authors: newbold a. J Biol Chem. 2005 Feb 11;280(6):4476-82. doi: 10.1074/jbc.M410985200. Epub 2004 Dec 1. J Biol Chem. 2005. PMID: 15574417 Free article.
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma.
Lindemann RK, Newbold A, Whitecross KF, Cluse LA, Frew AJ, Ellis L, Williams S, Wiegmans AP, Dear AE, Scott CL, Pellegrini M, Wei A, Richon VM, Marks PA, Lowe SW, Smyth MJ, Johnstone RW. Lindemann RK, et al. Among authors: newbold a. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8071-6. doi: 10.1073/pnas.0702294104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470784 Free PMC article.
The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.
Ellis L, Bots M, Lindemann RK, Bolden JE, Newbold A, Cluse LA, Scott CL, Strasser A, Atadja P, Lowe SW, Johnstone RW. Ellis L, et al. Among authors: newbold a. Blood. 2009 Jul 9;114(2):380-93. doi: 10.1182/blood-2008-10-182758. Epub 2009 Apr 21. Blood. 2009. PMID: 19383971 Free PMC article.
PIDDosome-independent tumor suppression by Caspase-2.
Manzl C, Peintner L, Krumschnabel G, Bock F, Labi V, Drach M, Newbold A, Johnstone R, Villunger A. Manzl C, et al. Among authors: newbold a. Cell Death Differ. 2012 Oct;19(10):1722-32. doi: 10.1038/cdd.2012.54. Epub 2012 May 18. Cell Death Differ. 2012. PMID: 22595758 Free PMC article.
43 results