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Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.
Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Grüner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, Sage J, Greenleaf WJ, Winslow MM. Denny SK, et al. Among authors: brady jj. Cell. 2016 Jul 14;166(2):328-342. doi: 10.1016/j.cell.2016.05.052. Epub 2016 Jun 30. Cell. 2016. PMID: 27374332 Free PMC article.
LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.
Pierce SE, Granja JM, Corces MR, Brady JJ, Tsai MK, Pierce AB, Tang R, Chu P, Feldser DM, Chang HY, Bassik MC, Greenleaf WJ, Winslow MM. Pierce SE, et al. Among authors: brady jj. Nat Cell Biol. 2021 Aug;23(8):915-924. doi: 10.1038/s41556-021-00728-4. Epub 2021 Aug 2. Nat Cell Biol. 2021. PMID: 34341533 Free PMC article.
Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin.
Yang D, Denny SK, Greenside PG, Chaikovsky AC, Brady JJ, Ouadah Y, Granja JM, Jahchan NS, Lim JS, Kwok S, Kong CS, Berghoff AS, Schmitt A, Reinhardt HC, Park KS, Preusser M, Kundaje A, Greenleaf WJ, Sage J, Winslow MM. Yang D, et al. Among authors: brady jj. Cancer Discov. 2018 Oct;8(10):1316-1331. doi: 10.1158/2159-8290.CD-17-0987. Epub 2018 Sep 18. Cancer Discov. 2018. PMID: 30228179 Free PMC article.
Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis.
Chuang CH, Greenside PG, Rogers ZN, Brady JJ, Yang D, Ma RK, Caswell DR, Chiou SH, Winters AF, Grüner BM, Ramaswami G, Spencley AL, Kopecky KE, Sayles LC, Sweet-Cordero EA, Li JB, Kundaje A, Winslow MM. Chuang CH, et al. Among authors: brady jj. Nat Med. 2017 Mar;23(3):291-300. doi: 10.1038/nm.4285. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191885 Free PMC article.
An LKB1-SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation.
Murray CW, Brady JJ, Tsai MK, Li C, Winters IP, Tang R, Andrejka L, Ma RK, Kunder CA, Chu P, Winslow MM. Murray CW, et al. Among authors: brady jj. Cancer Discov. 2019 Nov;9(11):1590-1605. doi: 10.1158/2159-8290.CD-18-1237. Epub 2019 Jul 26. Cancer Discov. 2019. PMID: 31350327 Free PMC article.
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.
Chiou SH, Winters IP, Wang J, Naranjo S, Dudgeon C, Tamburini FB, Brady JJ, Yang D, Grüner BM, Chuang CH, Caswell DR, Zeng H, Chu P, Kim GE, Carpizo DR, Kim SK, Winslow MM. Chiou SH, et al. Among authors: brady jj. Genes Dev. 2015 Jul 15;29(14):1576-85. doi: 10.1101/gad.264861.115. Epub 2015 Jul 15. Genes Dev. 2015. PMID: 26178787 Free PMC article.
75 results