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Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.
Nicod J, Davies RW, Cai N, Hassett C, Goodstadt L, Cosgrove C, Yee BK, Lionikaite V, McIntyre RE, Remme CA, Lodder EM, Gregory JS, Hough T, Joynson R, Phelps H, Nell B, Rowe C, Wood J, Walling A, Bopp N, Bhomra A, Hernandez-Pliego P, Callebert J, Aspden RM, Talbot NP, Robbins PA, Harrison M, Fray M, Launay JM, Pinto YM, Blizard DA, Bezzina CR, Adams DJ, Franken P, Weaver T, Wells S, Brown SD, Potter PK, Klenerman P, Lionikas A, Mott R, Flint J. Nicod J, et al. Among authors: hough t. Nat Genet. 2016 Aug;48(8):912-8. doi: 10.1038/ng.3595. Epub 2016 Jul 4. Nat Genet. 2016. PMID: 27376238 Free PMC article.
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.
Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. Nolan PM, et al. Among authors: hough t. Nat Genet. 2000 Aug;25(4):440-3. doi: 10.1038/78140. Nat Genet. 2000. PMID: 10932191
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
Solberg LC, Valdar W, Gauguier D, Nunez G, Taylor A, Burnett S, Arboledas-Hita C, Hernandez-Pliego P, Davidson S, Burns P, Bhattacharya S, Hough T, Higgs D, Klenerman P, Cookson WO, Zhang Y, Deacon RM, Rawlins JN, Mott R, Flint J. Solberg LC, et al. Among authors: hough t. Mamm Genome. 2006 Feb;17(2):129-46. doi: 10.1007/s00335-005-0112-1. Epub 2006 Feb 6. Mamm Genome. 2006. PMID: 16465593
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media.
Parkinson N, Hardisty-Hughes RE, Tateossian H, Tsai HT, Brooker D, Morse S, Lalane Z, MacKenzie F, Fray M, Glenister P, Woodward AM, Polley S, Barbaric I, Dear N, Hough TA, Hunter AJ, Cheeseman MT, Brown SD. Parkinson N, et al. Among authors: hough ta. PLoS Genet. 2006 Oct 6;2(10):e149. doi: 10.1371/journal.pgen.0020149. PLoS Genet. 2006. PMID: 17029558 Free PMC article.
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.
Pastorelli LM, Wells S, Fray M, Smith A, Hough T, Harfe BD, McManus MT, Smith L, Woolf AS, Cheeseman M, Greenfield A. Pastorelli LM, et al. Among authors: hough t. Mamm Genome. 2009 Mar;20(3):140-51. doi: 10.1007/s00335-008-9169-y. Epub 2009 Jan 24. Mamm Genome. 2009. PMID: 19169742
EuroPhenome: a repository for high-throughput mouse phenotyping data.
Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J; EUMODIC Consortium; de Angelis MH, Brown SD, Hancock JM, Mallon AM. Morgan H, et al. Nucleic Acids Res. 2010 Jan;38(Database issue):D577-85. doi: 10.1093/nar/gkp1007. Epub 2009 Nov 23. Nucleic Acids Res. 2010. PMID: 19933761 Free PMC article.
97 results