Agafonov DE - Search Results

1

ATPγS stalls splicing after B complex formation but prior to spliceosome activation.

Agafonov DE, van Santen M, Kastner B, Dube P, Will CL, Urlaub H, Lührmann R. Agafonov DE, et al. RNA. 2016 Sep;22(9):1329-37. doi: 10.1261/rna.057810.116. Epub 2016 Jul 13. RNA. 2016. PMID: 27411562 Free PMC article.

2

Molecular architecture of the human Prp19/CDC5L complex.

Grote M, Wolf E, Will CL, Lemm I, Agafonov DE, Schomburg A, Fischle W, Urlaub H, Lührmann R. Grote M, et al. Among authors: agafonov de. Mol Cell Biol. 2010 May;30(9):2105-19. doi: 10.1128/MCB.01505-09. Epub 2010 Feb 22. Mol Cell Biol. 2010. PMID: 20176811 Free PMC article.

3

Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method.

Agafonov DE, Deckert J, Wolf E, Odenwälder P, Bessonov S, Will CL, Urlaub H, Lührmann R. Agafonov DE, et al. Mol Cell Biol. 2011 Jul;31(13):2667-82. doi: 10.1128/MCB.05266-11. Epub 2011 May 2. Mol Cell Biol. 2011. PMID: 21536652 Free PMC article.

4

Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells.

Alló M, Agirre E, Bessonov S, Bertucci P, Gómez Acuña L, Buggiano V, Bellora N, Singh B, Petrillo E, Blaustein M, Miñana B, Dujardin G, Pozzi B, Pelisch F, Bechara E, Agafonov DE, Srebrow A, Lührmann R, Valcárcel J, Eyras E, Kornblihtt AR. Alló M, et al. Among authors: agafonov de. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15622-9. doi: 10.1073/pnas.1416858111. Epub 2014 Oct 13. Proc Natl Acad Sci U S A. 2014. PMID: 25313066 Free PMC article.

5

Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site.

Boesler C, Rigo N, Agafonov DE, Kastner B, Urlaub H, Will CL, Lührmann R. Boesler C, et al. Among authors: agafonov de. RNA. 2015 Nov;21(11):1993-2005. doi: 10.1261/rna.053991.115. Epub 2015 Sep 18. RNA. 2015. PMID: 26385511 Free PMC article.

6

Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes.

Schneider C, Agafonov DE, Schmitzová J, Hartmuth K, Fabrizio P, Lührmann R. Schneider C, et al. Among authors: agafonov de. PLoS Genet. 2015 Sep 22;11(9):e1005539. doi: 10.1371/journal.pgen.1005539. eCollection 2015. PLoS Genet. 2015. PMID: 26393790 Free PMC article.

7

Molecular architecture of the human U4/U6.U5 tri-snRNP.

Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H, Lührmann R, Stark H. Agafonov DE, et al. Science. 2016 Mar 25;351(6280):1416-20. doi: 10.1126/science.aad2085. Epub 2016 Feb 18. Science. 2016. PMID: 26912367

8

The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction.

Fourmann JB, Dybkov O, Agafonov DE, Tauchert MJ, Urlaub H, Ficner R, Fabrizio P, Lührmann R. Fourmann JB, et al. Among authors: agafonov de. Elife. 2016 Apr 26;5:e15564. doi: 10.7554/eLife.15564. Elife. 2016. PMID: 27115347 Free PMC article.

9

A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity.

Boesler C, Rigo N, Anokhina MM, Tauchert MJ, Agafonov DE, Kastner B, Urlaub H, Ficner R, Will CL, Lührmann R. Boesler C, et al. Among authors: agafonov de. Nat Commun. 2016 Jul 5;7:11997. doi: 10.1038/ncomms11997. Nat Commun. 2016. PMID: 27377154 Free PMC article.

10

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.

Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Lührmann R. Bertram K, et al. Among authors: agafonov de. Nature. 2017 Feb 16;542(7641):318-323. doi: 10.1038/nature21079. Epub 2017 Jan 11. Nature. 2017. PMID: 28076346

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