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Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.
Andreassen CN, Rosenstein BS, Kerns SL, Ostrer H, De Ruysscher D, Cesaretti JA, Barnett GC, Dunning AM, Dorling L, West CML, Burnet NG, Elliott R, Coles C, Hall E, Fachal L, Vega A, Gómez-Caamaño A, Talbot CJ, Symonds RP, De Ruyck K, Thierens H, Ost P, Chang-Claude J, Seibold P, Popanda O, Overgaard M, Dearnaley D, Sydes MR, Azria D, Koch CA, Parliament M, Blackshaw M, Sia M, Fuentes-Raspall MJ, Ramon Y Cajal T, Barnadas A, Vesprini D, Gutiérrez-Enríquez S, Mollà M, Díez O, Yarnold JR, Overgaard J, Bentzen SM, Alsner J; International Radiogenomics Consortium (RgC). Andreassen CN, et al. Among authors: thierens h. Radiother Oncol. 2016 Dec;121(3):431-439. doi: 10.1016/j.radonc.2016.06.017. Epub 2016 Jul 18. Radiother Oncol. 2016. PMID: 27443449 Free PMC article.
Acute radiation-induced nocturia in prostate cancer patients is associated with pretreatment symptoms, radical prostatectomy, and genetic markers in the TGFβ1 gene.
De Langhe S, De Ruyck K, Ost P, Fonteyne V, Werbrouck J, De Meerleer G, De Neve W, Thierens H. De Langhe S, et al. Among authors: thierens h. Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):393-9. doi: 10.1016/j.ijrobp.2012.02.061. Epub 2012 Jun 2. Int J Radiat Oncol Biol Phys. 2013. PMID: 22658438
Radiogenomics: radiobiology enters the era of big data and team science.
Rosenstein BS, West CM, Bentzen SM, Alsner J, Andreassen CN, Azria D, Barnett GC, Baumann M, Burnet N, Chang-Claude J, Chuang EY, Coles CE, Dekker A, De Ruyck K, De Ruysscher D, Drumea K, Dunning AM, Easton D, Eeles R, Fachal L, Gutiérrez-Enríquez S, Haustermans K, Henríquez-Hernández LA, Imai T, Jones GD, Kerns SL, Liao Z, Onel K, Ostrer H, Parliament M, Pharoah PD, Rebbeck TR, Talbot CJ, Thierens H, Vega A, Witte JS, Wong P, Zenhausern F; Radiogenomics Consortium. Rosenstein BS, et al. Among authors: thierens h. Int J Radiat Oncol Biol Phys. 2014 Jul 15;89(4):709-13. doi: 10.1016/j.ijrobp.2014.03.009. Int J Radiat Oncol Biol Phys. 2014. PMID: 24969789 Free PMC article. No abstract available.
Pitfalls in Prediction Modeling for Normal Tissue Toxicity in Radiation Therapy: An Illustration With the Individual Radiation Sensitivity and Mammary Carcinoma Risk Factor Investigation Cohorts.
Mbah C, Thierens H, Thas O, De Neve J, Chang-Claude J, Seibold P, Botma A, West C, De Ruyck K. Mbah C, et al. Among authors: thierens h. Int J Radiat Oncol Biol Phys. 2016 Aug 1;95(5):1466-1476. doi: 10.1016/j.ijrobp.2016.03.034. Epub 2016 Apr 1. Int J Radiat Oncol Biol Phys. 2016. PMID: 27479726
Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era.
Azria D, Lapierre A, Gourgou S, De Ruysscher D, Colinge J, Lambin P, Brengues M, Ward T, Bentzen SM, Thierens H, Rancati T, Talbot CJ, Vega A, Kerns SL, Andreassen CN, Chang-Claude J, West CML, Gill CM, Rosenstein BS. Azria D, et al. Among authors: thierens h. Front Oncol. 2017 Apr 27;7:83. doi: 10.3389/fonc.2017.00083. eCollection 2017. Front Oncol. 2017. PMID: 28497027 Free PMC article. Review.
252 results