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Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors.
J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):323-330. doi: 10.1016/j.jsbmb.2016.07.010. Epub 2016 Jul 26.
J Steroid Biochem Mol Biol. 2017.
PMID: 27471149
Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations.
Viktorsson EÖ, Gabrielsen M, Kumarachandran N, Sylte I, Rongved P, Åstrand OA, Kase ET.
Viktorsson EÖ, et al.
Steroids. 2017 Feb;118:119-127. doi: 10.1016/j.steroids.2016.12.003. Epub 2016 Dec 21.
Steroids. 2017.
PMID: 28011133
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Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hy-droxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetra-deca-hydro-1H-cyclo-penta[a]phenanthren-17-yl]-N-meth-oxy-N-methyl-pro-pan-amide (Fernholz Weinreb amide).
Viktorsson EØ, Åstrand OA, Haseeb RS, Görbitz CH, Rongved P.
Viktorsson EØ, et al.
Acta Crystallogr E Crystallogr Commun. 2015 Feb 18;71(Pt 3):275-7. doi: 10.1107/S2056989015001747. eCollection 2015 Mar 1.
Acta Crystallogr E Crystallogr Commun. 2015.
PMID: 25844186
Free PMC article.
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New prodrugs and analogs of the phenazine 5,10-dioxide natural products iodinin and myxin promote selective cytotoxicity towards human acute myeloid leukemia cells.
Viktorsson EÖ, Aesoy R, Støa S, Lekve V, Døskeland SO, Herfindal L, Rongved P.
Viktorsson EÖ, et al.
RSC Med Chem. 2021 Apr 19;12(5):767-778. doi: 10.1039/d1md00020a.
RSC Med Chem. 2021.
PMID: 34124675
Free PMC article.
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Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives.
Viktorsson EÖ, Melling Grøthe B, Aesoy R, Sabir M, Snellingen S, Prandina A, Høgmoen Åstrand OA, Bonge-Hansen T, Døskeland SO, Herfindal L, Rongved P.
Viktorsson EÖ, et al.
Bioorg Med Chem. 2017 Apr 1;25(7):2285-2293. doi: 10.1016/j.bmc.2017.02.058. Epub 2017 Feb 28.
Bioorg Med Chem. 2017.
PMID: 28284865
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