Tata J - Search Results

1

Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors.

Hanisak J, Seganish WM, McElroy WT, Tang H, Zhang R, Tsui HC, Fischmann T, Tulshian D, Tata J, Sondey C, Devito K, Fossetta J, Garlisi CG, Lundell D, Niu X. Hanisak J, et al. Among authors: tata j. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4250-5. doi: 10.1016/j.bmcl.2016.07.048. Epub 2016 Jul 22. Bioorg Med Chem Lett. 2016. PMID: 27476420

2

Highly potent, orally active diester macrocyclic human renin inhibitors.

Weber AE, Steiner MG, Krieter PA, Colletti AE, Tata JR, Halgren TA, Ball RG, Doyle JJ, Schorn TW, Stearns RA, et al. Weber AE, et al. Among authors: tata jr. J Med Chem. 1992 Oct 16;35(21):3755-73. doi: 10.1021/jm00099a004. J Med Chem. 1992. PMID: 1433190

3

Combinatorial diversification of indinavir: in vivo mixture dosing of an HIV protease inhibitor library.

Rano TA, Cheng Y, Huening TT, Zhang F, Schleif WA, Gabryelski L, Olsen DB, Kuo LC, Lin JH, Xu X, Olah TV, McLoughlin DA, King R, Chapman KT, Tata JR. Rano TA, et al. Among authors: tata jr. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1527-30. doi: 10.1016/s0960-894x(00)00276-6. Bioorg Med Chem Lett. 2000. PMID: 10915042

4

A combinatorial library of indinavir analogues and its in vitro and in vivo studies.

Cheng Y, Rano TA, Huening TT, Zhang F, Lu Z, Schleif WA, Gabryelski L, Olsen DB, Stahlhut M, Kuo LC, Lin JH, Xu X, Jin L, Olah TV, McLoughlin DA, King RC, Chapman KT, Tata JR. Cheng Y, et al. Bioorg Med Chem Lett. 2002 Feb 25;12(4):529-32. doi: 10.1016/s0960-894x(01)00824-1. Bioorg Med Chem Lett. 2002. PMID: 11844665

5

Indinavir analogues with blocked metabolism sites as HIV protease inhibitors with improved pharmacological profiles and high potency against PI-resistant viral strains.

Cheng Y, Zhang F, Rano TA, Lu Z, Schleif WA, Gabryelski L, Olsen DB, Stahlhut M, Rutkowski CA, Lin JH, Jin L, Emini EA, Chapman KT, Tata JR. Cheng Y, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2419-22. doi: 10.1016/s0960-894x(02)00424-9. Bioorg Med Chem Lett. 2002. PMID: 12161147

6

Synthesis and activity of novel HIV protease inhibitors with improved potency against multiple PI-resistant viral strains.

Duffy JL, Kevin NJ, Kirk BA, Chapman KT, Schleif WA, Olsen DB, Stahlhut M, Rutkowski CA, Kuo LC, Jin L, Lin JH, Emini EA, Tata JR. Duffy JL, et al. Among authors: tata jr. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2423-6. doi: 10.1016/s0960-894x(02)00425-0. Bioorg Med Chem Lett. 2002. PMID: 12161148

7

Combinatorial library of indinavir analogues: replacement for the aminoindanol at P2'.

Raghavan S, Yang Z, Mosley RT, Schleif WA, Gabryelski L, Olsen DB, Stahlhut M, Kuo LC, Emini EA, Chapman KT, Tata JR. Raghavan S, et al. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2855-8. doi: 10.1016/s0960-894x(02)00632-7. Bioorg Med Chem Lett. 2002. PMID: 12270162

8

Substituted bridged phenyl piperidines: orally active growth hormone secretagogues.

Lu Z, Tata JR, Cheng K, Wei L, Chan WW, Butler B, Schleim KD, Jacks TM, Hickey G, Patchett AA. Lu Z, et al. Bioorg Med Chem Lett. 2003 May 19;13(10):1817-20. doi: 10.1016/s0960-894x(03)00261-0. Bioorg Med Chem Lett. 2003. PMID: 12729672

9

Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus.

Lu Z, Raghavan S, Bohn J, Charest M, Stahlhut MW, Rutkowski CA, Simcoe AL, Olsen DB, Schleif WA, Carella A, Gabryelski L, Jin L, Lin JH, Emini E, Chapman K, Tata JR. Lu Z, et al. Among authors: tata jr. Bioorg Med Chem Lett. 2003 May 19;13(10):1821-4. doi: 10.1016/s0960-894x(03)00262-2. Bioorg Med Chem Lett. 2003. PMID: 12729673

10

HIV protease inhibitors with picomolar potency against PI-Resistant HIV-1 by extension of the P3 substituent.

Duffy JL, Rano TA, Kevin NJ, Chapman KT, Schleif WA, Olsen DB, Stahlhut M, Rutkowski CA, Kuo LC, Jin L, Lin JH, Emini EA, Tata JR. Duffy JL, et al. Among authors: tata jr. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2569-72. doi: 10.1016/s0960-894x(03)00475-x. Bioorg Med Chem Lett. 2003. PMID: 12852968

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