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Understanding human immune function using the resources from the Human Functional Genomics Project.
Netea MG, Joosten LA, Li Y, Kumar V, Oosting M, Smeekens S, Jaeger M, Ter Horst R, Schirmer M, Vlamakis H, Notebaart R, Pavelka N, Aguirre-Gamboa RR, Swertz MA, Tunjungputri RN, van de Heijden W, Franzosa EA, Ng A, Graham D, Lassen K, Schraa K, Netea-Maier R, Smit J, de Mast Q, van de Veerdonk F, Kullberg BJ, Tack C, van de Munckhof I, Rutten J, van der Graaf J, Franke L, Hofker M, Jonkers I, Platteel M, Maatman A, Fu J, Zhernakova A, van der Meer JW, Dinarello CA, van der Ven A, Huttenhouwer C, Koenen H, Joosten I, Xavier RJ, Wijmenga C. Netea MG, et al. Among authors: jaeger m. Nat Med. 2016 Aug 4;22(8):831-3. doi: 10.1038/nm.4140. Nat Med. 2016. PMID: 27490433 No abstract available.
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
Li Y, Oosting M, Smeekens SP, Jaeger M, Aguirre-Gamboa R, Le KTT, Deelen P, Ricaño-Ponce I, Schoffelen T, Jansen AFM, Swertz MA, Withoff S, van de Vosse E, van Deuren M, van de Veerdonk F, Zhernakova A, van der Meer JWM, Xavier RJ, Franke L, Joosten LAB, Wijmenga C, Kumar V, Netea MG. Li Y, et al. Among authors: jaeger m. Cell. 2016 Nov 3;167(4):1099-1110.e14. doi: 10.1016/j.cell.2016.10.017. Cell. 2016. PMID: 27814507 Free article.
The effect of host genetics on the gut microbiome.
Bonder MJ, Kurilshikov A, Tigchelaar EF, Mujagic Z, Imhann F, Vila AV, Deelen P, Vatanen T, Schirmer M, Smeekens SP, Zhernakova DV, Jankipersadsing SA, Jaeger M, Oosting M, Cenit MC, Masclee AA, Swertz MA, Li Y, Kumar V, Joosten L, Harmsen H, Weersma RK, Franke L, Hofker MH, Xavier RJ, Jonkers D, Netea MG, Wijmenga C, Fu J, Zhernakova A. Bonder MJ, et al. Among authors: jaeger m. Nat Genet. 2016 Nov;48(11):1407-1412. doi: 10.1038/ng.3663. Epub 2016 Oct 3. Nat Genet. 2016. PMID: 27694959
Host and Environmental Factors Influencing Individual Human Cytokine Responses.
Ter Horst R, Jaeger M, Smeekens SP, Oosting M, Swertz MA, Li Y, Kumar V, Diavatopoulos DA, Jansen AFM, Lemmers H, Toenhake-Dijkstra H, van Herwaarden AE, Janssen M, van der Molen RG, Joosten I, Sweep FCGJ, Smit JW, Netea-Maier RT, Koenders MMJF, Xavier RJ, van der Meer JWM, Dinarello CA, Pavelka N, Wijmenga C, Notebaart RA, Joosten LAB, Netea MG. Ter Horst R, et al. Among authors: jaeger m. Cell. 2016 Nov 3;167(4):1111-1124.e13. doi: 10.1016/j.cell.2016.10.018. Cell. 2016. PMID: 27814508 Free PMC article.
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.
Schirmer M, Smeekens SP, Vlamakis H, Jaeger M, Oosting M, Franzosa EA, Ter Horst R, Jansen T, Jacobs L, Bonder MJ, Kurilshikov A, Fu J, Joosten LAB, Zhernakova A, Huttenhower C, Wijmenga C, Netea MG, Xavier RJ. Schirmer M, et al. Among authors: jaeger m. Cell. 2016 Nov 3;167(4):1125-1136.e8. doi: 10.1016/j.cell.2016.10.020. Cell. 2016. PMID: 27814509 Free PMC article.
Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.
Oosting M, Kerstholt M, Ter Horst R, Li Y, Deelen P, Smeekens S, Jaeger M, Lachmandas E, Vrijmoeth H, Lupse M, Flonta M, Cramer RA, Kullberg BJ, Kumar V, Xavier R, Wijmenga C, Netea MG, Joosten LA. Oosting M, et al. Among authors: jaeger m. Cell Host Microbe. 2016 Dec 14;20(6):822-833. doi: 10.1016/j.chom.2016.10.006. Epub 2016 Nov 3. Cell Host Microbe. 2016. PMID: 27818078 Free article.
Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits.
Aguirre-Gamboa R, Joosten I, Urbano PCM, van der Molen RG, van Rijssen E, van Cranenbroek B, Oosting M, Smeekens S, Jaeger M, Zorro M, Withoff S, van Herwaarden AE, Sweep FCGJ, Netea RT, Swertz MA, Franke L, Xavier RJ, Joosten LAB, Netea MG, Wijmenga C, Kumar V, Li Y, Koenen HJPM. Aguirre-Gamboa R, et al. Among authors: jaeger m. Cell Rep. 2016 Nov 22;17(9):2474-2487. doi: 10.1016/j.celrep.2016.10.053. Epub 2016 Nov 3. Cell Rep. 2016. PMID: 27818087 Free PMC article.
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses.
Bakker OB, Aguirre-Gamboa R, Sanna S, Oosting M, Smeekens SP, Jaeger M, Zorro M, Võsa U, Withoff S, Netea-Maier RT, Koenen HJPM, Joosten I, Xavier RJ, Franke L, Joosten LAB, Kumar V, Wijmenga C, Netea MG, Li Y. Bakker OB, et al. Among authors: jaeger m. Nat Immunol. 2018 Jul;19(7):776-786. doi: 10.1038/s41590-018-0121-3. Epub 2018 May 21. Nat Immunol. 2018. PMID: 29784908 Free PMC article.
A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans.
Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y, Wijmenga C, Netea MG, Kumar V. Jaeger M, et al. J Infect Dis. 2019 Jul 31;220(5):862-872. doi: 10.1093/infdis/jiz206. J Infect Dis. 2019. PMID: 31241743 Free PMC article.
810 results