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RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.
Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. Ito Y, et al. Among authors: chen h. Science. 2016 Aug 5;353(6299):603-8. doi: 10.1126/science.aaf6803. Science. 2016. PMID: 27493188 Free PMC article.
Necroptosis and Cancer.
Najafov A, Chen H, Yuan J. Najafov A, et al. Among authors: chen h. Trends Cancer. 2017 Apr;3(4):294-301. doi: 10.1016/j.trecan.2017.03.002. Trends Cancer. 2017. PMID: 28451648 Free PMC article.
RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.
Ofengeim D, Mazzitelli S, Ito Y, DeWitt JP, Mifflin L, Zou C, Das S, Adiconis X, Chen H, Zhu H, Kelliher MA, Levin JZ, Yuan J. Ofengeim D, et al. Among authors: chen h. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8788-E8797. doi: 10.1073/pnas.1714175114. Epub 2017 Sep 13. Proc Natl Acad Sci U S A. 2017. PMID: 28904096 Free PMC article.
TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.
Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J. Xu D, et al. Among authors: chen h. Cell. 2018 Sep 6;174(6):1477-1491.e19. doi: 10.1016/j.cell.2018.07.041. Epub 2018 Aug 23. Cell. 2018. PMID: 30146158 Free PMC article.
Ivonescimab Plus Chemotherapy in Non-Small Cell Lung Cancer With EGFR Variant: A Randomized Clinical Trial.
HARMONi-A Study Investigators; Fang W, Zhao Y, Luo Y, Yang R, Huang Y, He Z, Zhao H, Li M, Li K, Song Q, Du X, Sun Y, Li W, Xu F, Wang Z, Yang K, Fan Y, Liu B, Zhao H, Hu Y, Jia L, Xu S, Yi T, Lv D, Lan H, Li M, Liang W, Wang Y, Yang H, Jia Y, Chen Y, Lu J, Feng J, Liu C, Zhou M, Zhou J, Liu X, Zhou N, He M, Dong X, Chen H, Chen Y, Su H, Li X, Zhang Z, Yang L, Cheng Y, Chen L, Hou X, Zhang Y, Guo J, Wang Z, Lu H, Wu D, Feng W, Li W, Huang J, Wang Y, Song X, Peng J, Liu L, Guo Y, Li W, Lu D, Hu M, Wang ZM, Li B, Xia M, Zhang L. HARMONi-A Study Investigators, et al. Among authors: chen h. JAMA. 2024 May 31. doi: 10.1001/jama.2024.10613. Online ahead of print. JAMA. 2024. PMID: 38820549
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