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RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.
Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. Ito Y, et al. Among authors: najafov a. Science. 2016 Aug 5;353(6299):603-8. doi: 10.1126/science.aaf6803. Science. 2016. PMID: 27493188 Free PMC article.
Necroptosis and Cancer.
Najafov A, Chen H, Yuan J. Najafov A, et al. Trends Cancer. 2017 Apr;3(4):294-301. doi: 10.1016/j.trecan.2017.03.002. Trends Cancer. 2017. PMID: 28451648 Free PMC article.
Necroptosis in development and diseases.
Shan B, Pan H, Najafov A, Yuan J. Shan B, et al. Among authors: najafov a. Genes Dev. 2018 Mar 1;32(5-6):327-340. doi: 10.1101/gad.312561.118. Genes Dev. 2018. PMID: 29593066 Free PMC article. Review.
Activation of necroptosis in multiple sclerosis.
Ofengeim D, Ito Y, Najafov A, Zhang Y, Shan B, DeWitt JP, Ye J, Zhang X, Chang A, Vakifahmetoglu-Norberg H, Geng J, Py B, Zhou W, Amin P, Berlink Lima J, Qi C, Yu Q, Trapp B, Yuan J. Ofengeim D, et al. Among authors: najafov a. Cell Rep. 2015 Mar 24;10(11):1836-49. doi: 10.1016/j.celrep.2015.02.051. Cell Rep. 2015. PMID: 25801023 Free PMC article.
RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Najafov A, Luu HS, Mookhtiar AK, Mifflin L, Xia HG, Amin PP, Ordureau A, Wang H, Yuan J. Najafov A, et al. Mol Cell. 2021 Jan 21;81(2):370-385.e7. doi: 10.1016/j.molcel.2020.11.008. Epub 2020 Dec 2. Mol Cell. 2021. PMID: 33271062 Free article.
36 results