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Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1.
Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL, Chao CH, Yamaguchi H, Yang NK, Ding Q, Wang Y, Lai YJ, LaBaff AM, Wu TJ, Lin BR, Yang MH, Hortobagyi GN, Hung MC. Li CW, et al. Among authors: labaff am. Cancer Res. 2012 Mar 1;72(5):1290-300. doi: 10.1158/0008-5472.CAN-11-3123. Epub 2012 Jan 17. Cancer Res. 2012. PMID: 22253230 Free PMC article.
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Wang Y, Ding Q, Yen CJ, Xia W, Izzo JG, Lang JY, Li CW, Hsu JL, Miller SA, Wang X, Lee DF, Hsu JM, Huo L, Labaff AM, Liu D, Huang TH, Lai CC, Tsai FJ, Chang WC, Chen CH, Wu TT, Buttar NS, Wang KK, Wu Y, Wang H, Ajani J, Hung MC. Wang Y, et al. Among authors: labaff am. Cancer Cell. 2012 Mar 20;21(3):374-87. doi: 10.1016/j.ccr.2011.12.028. Cancer Cell. 2012. PMID: 22439934 Free PMC article.
AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.
Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, Wang Y, Chou CK, Hsu JM, Lai YJ, LaBaff AM, Ding Q, Ko HW, Tsai FJ, Tsai CH, Hortobagyi GN, Hung MC. Li CW, et al. Among authors: labaff am. Cancer Res. 2016 Mar 15;76(6):1451-62. doi: 10.1158/0008-5472.CAN-15-1941. Epub 2016 Jan 12. Cancer Res. 2016. PMID: 26759241 Free PMC article.
Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth.
Werden SJ, Sphyris N, Sarkar TR, Paranjape AN, LaBaff AM, Taube JH, Hollier BG, Ramirez-Peña EQ, Soundararajan R, den Hollander P, Powell E, Echeverria GV, Miura N, Chang JT, Piwnica-Worms H, Rosen JM, Mani SA. Werden SJ, et al. Among authors: labaff am. Oncogene. 2016 Nov 17;35(46):5977-5988. doi: 10.1038/onc.2016.203. Epub 2016 Jun 13. Oncogene. 2016. PMID: 27292262 Free PMC article.