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Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases.
Heidari M, Gerami SH, Bassett B, Graham RM, Chua AC, Aryal R, House MJ, Collingwood JF, Bettencourt C, Houlden H, Ryten M; UK Brain Expression Consortium (UKBEC); Olynyk JK, Trinder D, Johnstone DM, Milward EA. Heidari M, et al. Among authors: collingwood jf. Rare Dis. 2016 Jun 22;4(1):e1198458. doi: 10.1080/21675511.2016.1198458. eCollection 2016. Rare Dis. 2016. PMID: 27500074 Free PMC article.
Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features.
Heidari M, Johnstone DM, Bassett B, Graham RM, Chua AC, House MJ, Collingwood JF, Bettencourt C, Houlden H, Ryten M, Olynyk JK, Trinder D, Milward EA. Heidari M, et al. Among authors: collingwood jf. Mol Psychiatry. 2016 Nov;21(11):1599-1607. doi: 10.1038/mp.2015.192. Epub 2016 Jan 5. Mol Psychiatry. 2016. PMID: 26728570 Free PMC article.
Gene co-expression networks shed light into diseases of brain iron accumulation.
Bettencourt C, Forabosco P, Wiethoff S, Heidari M, Johnstone DM, Botía JA, Collingwood JF, Hardy J; UK Brain Expression Consortium (UKBEC); Milward EA, Ryten M, Houlden H. Bettencourt C, et al. Among authors: collingwood jf. Neurobiol Dis. 2016 Mar;87:59-68. doi: 10.1016/j.nbd.2015.12.004. Epub 2015 Dec 18. Neurobiol Dis. 2016. PMID: 26707700 Free PMC article.
Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues.
Everett J, Brooks J, Tjendana Tjhin V, Lermyte F, Hands-Portman I, Plascencia-Villa G, Perry G, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Everett J, et al. Among authors: collingwood jf. ACS Chem Neurosci. 2024 Apr 3;15(7):1469-1483. doi: 10.1021/acschemneuro.3c00756. Epub 2024 Mar 19. ACS Chem Neurosci. 2024. PMID: 38501754 Free PMC article.
Biogenic metallic elements in the human brain?
Everett J, Lermyte F, Brooks J, Tjendana-Tjhin V, Plascencia-Villa G, Hands-Portman I, Donnelly JM, Billimoria K, Perry G, Zhu X, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Everett J, et al. Among authors: collingwood jf. Sci Adv. 2021 Jun 9;7(24):eabf6707. doi: 10.1126/sciadv.abf6707. Print 2021 Jun. Sci Adv. 2021. PMID: 34108207 Free PMC article.
Cu(III)-bis-thiolato complex forms an unusual mono-thiolato Cu(III)-peroxido adduct.
Donnelly JM , Lermyte F , Wolny JA , Walker M , Breeze BG , Needham RJ , Müller CS , O'Connor PB , Schünemann V , Collingwood JF , Sadler PJ . Donnelly JM , et al. Among authors: collingwood jf. Chem Commun (Camb). 2021 Jan 5;57(1):69-72. doi: 10.1039/d0cc06921c. Chem Commun (Camb). 2021. PMID: 33337460
34 results