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Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis.
Yang JD, Abdelmalek MF, Guy CD, Gill RM, Lavine JE, Yates K, Klair J, Terrault NA, Clark JM, Unalp-Arida A, Diehl AM, Suzuki A; Nonalcoholic Steatohepatitis Clinical Research Network. Yang JD, et al. Among authors: yates k. Clin Gastroenterol Hepatol. 2017 Jan;15(1):127-131.e2. doi: 10.1016/j.cgh.2016.07.034. Epub 2016 Aug 12. Clin Gastroenterol Hepatol. 2017. PMID: 27523635 Free PMC article.
The Nimble Stage 1 Study Validates Diagnostic Circulating Biomarkers for Nonalcoholic Steatohepatitis.
Sanyal A, Shankar S, Yates K, Bolognese J, Daly E, Dehn C, Neuschwander-Tetri B, Kowdley K, Vuppalanchi R, Behling CA, Tonascia J, Samir A, Sirlin C, Sherlock S, Fowler K, Heymann H, Kamphaus T, Loomba R, Calle R. Sanyal A, et al. Among authors: yates k. Res Sq [Preprint]. 2023 Jan 19:rs.3.rs-2492725. doi: 10.21203/rs.3.rs-2492725/v1. Res Sq. 2023. PMID: 36711803 Free PMC article. Updated. Preprint.
Low MBOAT7 expression, a genetic risk for MASH, promotes a pro-fibrotic pathway involving hepatocyte TAZ upregulation.
Moore MP, Wang X, Kennelly JP, Shi H, Ishino Y, Kano K, Aoki J, Cherubini A, Ronzoni L, Guo X, Chalasani NP, Khalid S, Saleheen D, Mitsche MA, Rotter JI, Yates KP, Valenti L, Kono N, Tontonoz P, Tabas I. Moore MP, et al. Among authors: yates kp. Hepatology. 2024 May 22. doi: 10.1097/HEP.0000000000000933. Online ahead of print. Hepatology. 2024. PMID: 38776184
Renal impairment is prevalent in pediatric NAFLD/MASLD and associated with disease severity.
Mouzaki M, Yates KP, Arce-Clachar AC, Behling C, Blondet NM, Fishbein MH, Flores F, Adams KH, Hertel P, Jain AK, Molleston JP, Schwimmer JB, Vos MB, Xanthakos SA; NASH Clinical Research Network. Mouzaki M, et al. Among authors: yates kp. J Pediatr Gastroenterol Nutr. 2024 Jun 3. doi: 10.1002/jpn3.12272. Online ahead of print. J Pediatr Gastroenterol Nutr. 2024. PMID: 38828720
Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.
Senkpeil L, Bhardwaj J, Little MR, Holla P, Upadhye A, Fusco EM, Swanson Ii PA, Wiegand RE, Macklin MD, Bi K, Flynn BJ, Yamamoto A, Gaskin EL, Sather DN, Oblak AL, Simpson E, Gao H, Haining WN, Yates KB, Liu X, Murshedkar T, Richie TL, Sim BKL, Otieno K, Kariuki S, Xuei X, Liu Y, Polidoro RB, Hoffman SL, Oneko M, Steinhardt LC, Schmidt NW, Seder RA, Tran TM. Senkpeil L, et al. Among authors: yates kb. JCI Insight. 2024 Apr 30:e167408. doi: 10.1172/jci.insight.167408. Online ahead of print. JCI Insight. 2024. PMID: 38687615 Free article.
PNPLA3 rs738409, age, diabetes, sex, and advanced fibrosis jointly contribute to the risk of major adverse liver outcomes in metabolic-associated steatotic liver disease.
Chalasani N, Vilar-Gomez E, Loomba R, Yates KP, Diehl AM, Neuschwander-Tetri BA, Dasarathy S, Kowdley KV, Terrault N, Wilson LA, Tonascia J, Sanyal A. Chalasani N, et al. Among authors: yates kp. Hepatology. 2024 Apr 23. doi: 10.1097/HEP.0000000000000896. Online ahead of print. Hepatology. 2024. PMID: 38652636
Non-Hispanic Black persons with nonalcoholic fatty liver disease have lower rates of advanced fibrosis, cirrhosis, and liver-related events even after controlling for clinical risk factors and PNPLA3 genotype.
Samala N, Xin Y, Wilson LA, Yates K, Loomba R, Hoofnagle JH, Chalasani N; NASH Clinical Research Network. Samala N, et al. Among authors: yates k. Am J Gastroenterol. 2024 Mar 14. doi: 10.14309/ajg.0000000000002756. Online ahead of print. Am J Gastroenterol. 2024. PMID: 38483303
483 results