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Expression of DRD2 Is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice.
Jandaghi P, Najafabadi HS, Bauer AS, Papadakis AI, Fassan M, Hall A, Monast A, von Knebel Doeberitz M, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Sipos B, Auld D, Lathrop M, Park M, Büchler MW, Strobel O, Hackert T, Giese NA, Zogopoulos G, Sangwan V, Huang S, Riazalhosseini Y, Hoheisel JD. Jandaghi P, et al. Among authors: najafabadi hs. Gastroenterology. 2016 Dec;151(6):1218-1231. doi: 10.1053/j.gastro.2016.08.040. Epub 2016 Aug 28. Gastroenterology. 2016. PMID: 27578530
A General Framework for Interrogation of mRNA Stability Programs Identifies RNA-Binding Proteins that Govern Cancer Transcriptomes.
Perron G, Jandaghi P, Solanki S, Safisamghabadi M, Storoz C, Karimzadeh M, Papadakis AI, Arseneault M, Scelo G, Banks RE, Tost J, Lathrop M, Tanguay S, Brazma A, Huang S, Brimo F, Najafabadi HS, Riazalhosseini Y. Perron G, et al. Among authors: najafabadi hs. Cell Rep. 2018 May 8;23(6):1639-1650. doi: 10.1016/j.celrep.2018.04.031. Cell Rep. 2018. PMID: 29742422 Free article.
Aberration hubs in protein interaction networks highlight actionable targets in cancer.
Karimzadeh M, Jandaghi P, Papadakis AI, Trainor S, Rung J, Gonzàlez-Porta M, Scelo G, Vasudev NS, Brazma A, Huang S, Banks RE, Lathrop M, Najafabadi HS, Riazalhosseini Y. Karimzadeh M, et al. Among authors: najafabadi hs. Oncotarget. 2018 May 18;9(38):25166-25180. doi: 10.18632/oncotarget.25382. eCollection 2018 May 18. Oncotarget. 2018. PMID: 29861861 Free PMC article.
Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles.
Tawil N, Bassawon R, Meehan B, Nehme A, Montermini L, Gayden T, De Jay N, Spinelli C, Chennakrishnaiah S, Choi D, Adnani L, Zeinieh M, Jabado N, Kleinman CL, Witcher M, Riazalhosseini Y, Key NS, Schiff D, Grover SP, Mackman N, Couturier CP, Petrecca K, Suvà ML, Patel A, Tirosh I, Najafabadi H, Rak J. Tawil N, et al. Blood Adv. 2021 Mar 23;5(6):1682-1694. doi: 10.1182/bloodadvances.2020002998. Blood Adv. 2021. PMID: 33720339 Free PMC article.
An integrated model of acinar to ductal metaplasia-related N7-methyladenosine regulators predicts prognosis and immunotherapy in pancreatic carcinoma based on digital spatial profiling.
Yang H, Messina-Pacheco J, Corredor ALG, Gregorieff A, Liu JL, Nehme A, Najafabadi HS, Riazalhosseini Y, Gao B, Gao ZH. Yang H, et al. Among authors: najafabadi hs. Front Immunol. 2022 Jul 28;13:961457. doi: 10.3389/fimmu.2022.961457. eCollection 2022. Front Immunol. 2022. PMID: 35979350 Free PMC article.
Multi-omic analysis reveals significantly mutated genes and DDX3X as a sex-specific tumor suppressor in cutaneous melanoma.
Alkallas R, Lajoie M, Moldoveanu D, Hoang KV, Lefrançois P, Lingrand M, Ahanfeshar-Adams M, Watters K, Spatz A, Zippin JH, Najafabadi HS, Watson IR. Alkallas R, et al. Among authors: najafabadi hs. Nat Cancer. 2020 Jun;1(6):635-652. doi: 10.1038/s43018-020-0077-8. Epub 2020 Jun 22. Nat Cancer. 2020. PMID: 35121978 Free PMC article.
Analysis of mRNA Dynamics Using RNA Sequencing Data.
Alkallas R, Najafabadi HS. Alkallas R, et al. Among authors: najafabadi hs. Methods Mol Biol. 2022;2515:129-150. doi: 10.1007/978-1-0716-2409-8_9. Methods Mol Biol. 2022. PMID: 35776350
63 results