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Small-molecule WNK inhibition regulates cardiovascular and renal function.
Nat Chem Biol. 2016 Nov;12(11):896-898. doi: 10.1038/nchembio.2168. Epub 2016 Sep 5.
Nat Chem Biol. 2016.
PMID: 27595330
Directed evolution by accumulating tailored mutations: thermostabilization of lactate oxidase with less trade-off with catalytic activity.
Hamamatsu N, Nomiya Y, Aita T, Nakajima M, Husimi Y, Shibanaka Y.
Hamamatsu N, et al.
Protein Eng Des Sel. 2006 Nov;19(11):483-9. doi: 10.1093/protein/gzl034. Epub 2006 Sep 2.
Protein Eng Des Sel. 2006.
PMID: 16951411
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Biased mutation-assembling: an efficient method for rapid directed evolution through simultaneous mutation accumulation.
Hamamatsu N, Aita T, Nomiya Y, Uchiyama H, Nakajima M, Husimi Y, Shibanaka Y.
Hamamatsu N, et al.
Protein Eng Des Sel. 2005 Jun;18(6):265-71. doi: 10.1093/protein/gzi028. Epub 2005 May 31.
Protein Eng Des Sel. 2005.
PMID: 15928005
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Surveying a local fitness landscape of a protein with epistatic sites for the study of directed evolution.
Aita T, Hamamatsu N, Nomiya Y, Uchiyama H, Shibanaka Y, Husimi Y.
Aita T, et al. Among authors: hamamatsu n.
Biopolymers. 2002 Jul 5;64(2):95-105. doi: 10.1002/bip.10126.
Biopolymers. 2002.
PMID: 11979520
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Modified substrate specificity of pyrroloquinoline quinone glucose dehydrogenase by biased mutation assembling with optimized amino acid substitution.
Hamamatsu N, Suzumura A, Nomiya Y, Sato M, Aita T, Nakajima M, Husimi Y, Shibanaka Y.
Hamamatsu N, et al.
Appl Microbiol Biotechnol. 2006 Dec;73(3):607-17. doi: 10.1007/s00253-006-0521-4. Epub 2006 Aug 31.
Appl Microbiol Biotechnol. 2006.
PMID: 16944137
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[Two cases of metastasis of unknown origin syndrome: confirmed gallbladder origin by autopsy].
Sakamoto M, Serizawa H, Hibi T, Tsuzuki Y, Hamamatsu N, Miura S, Ishii H, Kitajima M, Torikata C, Tsuchiya M.
Sakamoto M, et al. Among authors: hamamatsu n.
Nihon Shokakibyo Gakkai Zasshi. 1994 Apr;91(4):938-43.
Nihon Shokakibyo Gakkai Zasshi. 1994.
PMID: 8170066
Japanese.
No abstract available.
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