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Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells.
Morin A, Kwan T, Ge B, Letourneau L, Ban M, Tandre K, Caron M, Sandling JK, Carlsson J, Bourque G, Laprise C, Montpetit A, Syvanen AC, Ronnblom L, Sawcer SJ, Lathrop MG, Pastinen T. Morin A, et al. Among authors: pastinen t. BMC Med Genomics. 2016 Sep 13;9(1):59. doi: 10.1186/s12920-016-0220-7. BMC Med Genomics. 2016. PMID: 27624058 Free PMC article.
A survey of genetic and epigenetic variation affecting human gene expression.
Pastinen T, Sladek R, Gurd S, Sammak A, Ge B, Lepage P, Lavergne K, Villeneuve A, Gaudin T, Brändström H, Beck A, Verner A, Kingsley J, Harmsen E, Labuda D, Morgan K, Vohl MC, Naumova AK, Sinnett D, Hudson TJ. Pastinen T, et al. Physiol Genomics. 2004 Jan 15;16(2):184-93. doi: 10.1152/physiolgenomics.00163.2003. Physiol Genomics. 2004. PMID: 14583597
Survey of allelic expression using EST mining.
Ge B, Gurd S, Gaudin T, Dore C, Lepage P, Harmsen E, Hudson TJ, Pastinen T. Ge B, et al. Among authors: pastinen t. Genome Res. 2005 Nov;15(11):1584-91. doi: 10.1101/gr.4023805. Genome Res. 2005. PMID: 16251468 Free PMC article.
Mapping common regulatory variants to human haplotypes.
Pastinen T, Ge B, Gurd S, Gaudin T, Dore C, Lemire M, Lepage P, Harmsen E, Hudson TJ. Pastinen T, et al. Hum Mol Genet. 2005 Dec 15;14(24):3963-71. doi: 10.1093/hmg/ddi420. Epub 2005 Nov 21. Hum Mol Genet. 2005. PMID: 16301213
Mapping cis-acting regulatory variation in recombinant congenic strains.
Lee PD, Ge B, Greenwood CM, Sinnett D, Fortin Y, Brunet S, Fortin A, Takane M, Skamene E, Pastinen T, Hallett M, Hudson TJ, Sladek R. Lee PD, et al. Among authors: pastinen t. Physiol Genomics. 2006 Apr 13;25(2):294-302. doi: 10.1152/physiolgenomics.00168.2005. Epub 2006 Jan 31. Physiol Genomics. 2006. PMID: 16449383
Association study between the CX3CR1 gene and asthma.
Tremblay K, Lemire M, Provost V, Pastinen T, Renaud Y, Sandford AJ, Laviolette M, Hudson TJ, Laprise C. Tremblay K, et al. Among authors: pastinen t. Genes Immun. 2006 Dec;7(8):632-9. doi: 10.1038/sj.gene.6364340. Epub 2006 Nov 2. Genes Immun. 2006. PMID: 17082760
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.
Sigurdsson S, Nordmark G, Garnier S, Grundberg E, Kwan T, Nilsson O, Eloranta ML, Gunnarsson I, Svenungsson E, Sturfelt G, Bengtsson AA, Jönsen A, Truedsson L, Rantapää-Dahlqvist S, Eriksson C, Alm G, Göring HH, Pastinen T, Syvänen AC, Rönnblom L. Sigurdsson S, et al. Among authors: pastinen t. Hum Mol Genet. 2008 Sep 15;17(18):2868-76. doi: 10.1093/hmg/ddn184. Epub 2008 Jun 25. Hum Mol Genet. 2008. PMID: 18579578 Free PMC article.
Targeted screening of cis-regulatory variation in human haplotypes.
Verlaan DJ, Ge B, Grundberg E, Hoberman R, Lam KC, Koka V, Dias J, Gurd S, Martin NW, Mallmin H, Nilsson O, Harmsen E, Dewar K, Kwan T, Pastinen T. Verlaan DJ, et al. Among authors: pastinen t. Genome Res. 2009 Jan;19(1):118-27. doi: 10.1101/gr.084798.108. Epub 2008 Oct 29. Genome Res. 2009. PMID: 18971308 Free PMC article.
228 results